• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Updates in Surgery >Adrenal metastases from adenocarcinoma of the esophagogastric junction: adrenalectomy and long-term survival
【24h】

Adrenal metastases from adenocarcinoma of the esophagogastric junction: adrenalectomy and long-term survival

机译：食管胃交界处腺癌的肾上腺转移：肾上腺切除术和长期生存

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Treatment of adrenal metastases from cancer of the esophagogastric junction (EGJ) is not defined. The aim of the present work is to analyze retrospectively our experience in treating patients with adrenal metastases from EGJ adenocarcinoma. 102 patients with Siewert 1 or 2 EGJ adenocarcinoma underwent esophagectomy between May 2001 and Jan 2009. Five patients were diagnosed an adrenal metastases from EGJ adenocarcinoma, synchronous (s) in one and metachronous (m) in four, in the latter 11 months (mean) after esophagectomy. At diagnosis, three patients had synchronous metastases to mediastinal nodes (1 s and 2 m), 1 (m) had synchronous metastases to bone, and 1 (m) had an isolated adrenal metastasis. Three patients with synchronous node metastasis received chemotherapy followed by adrenalectomy 3, 8 and 16 months (mean 9) after diagnosis; one patient also received postoperative mediastinal radiotherapy. These patients are alive with no evidence of disease 16, 40 and 50 months after diagnosis of adrenal metastasis. The patient with bone metastasis received chemotherapy only and died 12 months after diagnosis of metastatic disease. The patient with isolated metastasis underwent laparoscopic adrenalectomy only, developed early bone metastases and died 15 months after surgery. In conclusion, our experience indicates that patients with adrenal metastases from adenocarcinoma of the EGJ may benefit from adrenalectomy if the gland is the only site of metastasis beyond lymphnodal disease. Chemotherapy should be considered before adrenalectomy to achieve better disease control and identify aggressive disease that would contraindicate adrenalectomy.
机译：食管胃交界处（EGJ）癌症引起的肾上腺转移的治疗方法尚未明确。本工作的目的是回顾性分析我们治疗EGJ腺癌肾上腺转移患者的经验。在2001年5月至2009年1月之间，对102例Siewert 1或2 EGJ腺癌患者进行了食管切除术。在随后的11个月中，有5例被诊断为EGJ腺癌发生了肾上腺转移，其中一个为同步发生，四个为异时转移（m）。 ）。在诊断时，三名患者发生了纵隔淋巴结转移（1 s和2 m），1（m）发生了骨转移同步，1（m）发生了孤立的肾上腺转移。 3例同步淋巴结转移的患者在诊断后3、8和16个月（平均9）接受了化疗，随后进行了肾上腺切除术；一名患者还接受了术后纵隔放疗。这些患者在诊断出肾上腺转移后16、40和50个月都没有任何疾病的迹象。骨转移患者仅接受化疗，并在诊断出转移性疾病后死亡12个月。单纯转移的患者仅接受腹腔镜肾上腺切除术，发展为早期骨转移并在手术后15个月死亡。总之，我们的经验表明，如果腺体是淋巴结疾病以外唯一的转移部位，那么来自EGJ腺癌的肾上腺转移患者可能会受益于肾上腺切除术。肾上腺切除术前应考虑化学疗法，以更好地控制疾病并确定会禁止肾上腺切除术的侵袭性疾病。

著录项

  • 来源
    《Updates in Surgery》 |2010年第1期|63-67|共5页
  • 作者

    Uberto Fumagalli; Stefano de Carli; Stefano de Pascale; Lorenza Rimassa; Mario Bignardi; Riccardo Rosati;

  • 作者单位

    Department of General and Minimally Invasive Surgery Istituto Clinico Humanitas IRCCS Via Manzoni 56 20089 Rozzano (MI) Italy;

    Department of General and Minimally Invasive Surgery Istituto Clinico Humanitas IRCCS Via Manzoni 56 20089 Rozzano (MI) Italy;

    Department of General and Minimally Invasive Surgery Istituto Clinico Humanitas IRCCS Via Manzoni 56 20089 Rozzano (MI) Italy;

    Department of Medical Oncology and Hematology Istituto Clinico Humanitas IRCCS Rozzano (MI) Italy;

    Department of Radiotherapy Istituto Clinico Humanitas IRCCS Rozzano (MI) Italy;

    Department of General and Minimally Invasive Surgery Istituto Clinico Humanitas IRCCS Via Manzoni 56 20089 Rozzano (MI) Italy;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Adenocarcinoma; Esophagogastric junction; Adrenal metastases; Adrenalectomy;

    机译：腺癌;食管胃交界处;肾上腺转移;肾上腺切除术;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号