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Degraded Vi Strains' and Variation in Vi-phage II of Salmonella typhi

机译:降解VI菌株'和Salmonella Typhi的VI-Phage II的变化

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SUMMARY: The propagation of Vi-phage II on ‘degraded Vi strains’ of Salmonella typhi did not yield phage preparations bearing any trace of the specificity of the original Vi type from which the degraded strains had sprung.Ten different standard Vi-typing phages were grown on a selection of degraded Vi strains. The phages could be separated into two groups: six underwent a change which appeared to be a phenotypic modification, and four were propagated unchanged. It seems probable, however, that all adapted Vi-typing preparations are phenotypic modifications of Vi-phage II.In the attack of Vi-phage II on the typhoid bacillus the Vi antigen apparently plays a part only in the adsorption of the phage. The stages of phage growth succeeding adsorption seem to be independent of the Vi antigen, and it is in the regions of the bacterial cell concerned with these stages that Vi-type specificity seems to reside.
机译:发明内容:vi-phage II对沙门氏菌的“降解的vi菌株”的繁殖并未产生噬菌体制剂,其中含有任何痕迹的原始VI型特异性,从中增生的菌株浇花。国家不同标准的VI键入噬菌体在一系列退化的VI菌株中成长。该噬菌体可以分为两组:六次进行了似乎是表型修饰的变化,并且四个被繁殖不变。然而,似乎可能是所有适应的VI键入制剂是VI-phage II的表型修饰。在抗蛋白杆菌上的VI噬菌体II对抗碱杆菌的发作显然仅在噬菌体的吸附中发挥作用。噬菌体生长后续吸附的阶段似乎与VI抗原无关,并且它位于细菌细胞的区域,涉及这些阶段的VI型特异性似乎存在。

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  • 来源
    《Microbiology》 |1953年第3期|共13页
  • 作者

    E. S. Anderson; A. Felix;

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  • 收录信息 美国《科学引文索引》(SCI);
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