SUMMARY: Staphylococci may produce β-toxin and staphylokinase (fibrinolysin). In clinical material there is a preponderance of strains which are β-toxin negative and kinase positive (β-K-), but β+K-, β-K- and β+K+ strains also occur. Strains which are β+K- can be converted by lysogenization with certain phages to loss of β-toxin and gain of kinase (β-K+). This is true conversion, since every lysogenized coccus carries the new characters. All the phages which produced this double conversion (β-K+ phages) belong to the serological group F. The conversion is due to two separate loci on the phage which are active in the prophage state. These loci have not been found in phages of other serological groups (β°K° phages). The β-toxic and fibrinolytic properties of staphylococci are not always phage-dependent; strains which do not carry detectable phages or carry only β°K° phages can be either β+K-, β-K+, β+K+ or β-K-, implying the occurrence of structural loci on the bacterial genome. Several strains with the phage-typing pattern 80/81 or a related pattern, which are β-K+, were found to carry converting phages. On loss of these phages the strains became β+K- and showed a change of typing-pattern, gaining sensitivity for phages of group III.
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机译：发明内容：葡萄球菌可以产生β-毒素和葡萄球菌素（纤维蛋白酶）。在临床材料中，存在β-毒素阴性和激酶阳性（β-k-）的菌株的优势，但也发生β+ k-，β-k-和β+ k +株。 β+ k-的菌株可以通过用某些噬菌体转化的溶酶体，以丧失β-毒素和激酶（β-k +）的增益。这是真正的转换，因为每个溶血性的Coccus都带有新角色。产生这种双转化率（β-K +噬菌体）的所有噬菌体属于血清学组F.转化率是由于噬菌体中有效的两个单独的基因座，在前态。这些基因座未发现在其他血清学基团（β°k°噬菌体）的噬菌体中。葡萄球菌的β-毒性和纤维蛋白溶解性能并不总是含噬菌体;不携带可检测噬菌体或仅携带β°K°噬菌体的菌株可以是β+ k-，β-k +，β+ k +或β-k-，这意味着在细菌基因组上发生结构基因座。发现几种具有噬菌体键入图案80/81的菌株或是β-k +的相关图案，用于携带转换噬菌体。关于这些噬菌体的损失，菌株成为β+ k-并显示出典型模式的变化，获得III组噬菌体噬菌体的敏感性。
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