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首页> 外文期刊>Journal of Virology >Physical, Biochemical, and Immunological Properties of Coliphage MS-2 Particles
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Physical, Biochemical, and Immunological Properties of Coliphage MS-2 Particles

机译：Coliphage MS-2颗粒的物理，生化和免疫学特性

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H (heavy) and L (light) MS-2 particles differ in density, absorption spectrum, and infectivity. Studies on their sedimentation, ribonucleic acid (RNA) content and infectivity, appearance under the electron microscope, ribonuclease sensitivity, and A-protein content failed to demonstrate any difference between the two particle types. Studies on the size, RNA content, and density of the capsid and two smaller coat protein components were also conducted. The antigenic relatedness of five different viral and subviral particles of MS-2 were studied by using immunodiffusion and neutralization. Capsids and the H and L viral particles were shown to be antigenically related, whereas the coat protein monomers and dimers were shown to be unrelated to the higher-molecular-weight particles.
机译：H（重）和L（光）MS-2颗粒的密度，吸收光谱和感染性不同。研究其沉降，核糖核酸（RNA）含量和感染性，电子显微镜下的外观，核糖核酸核糖酶敏感性和蛋白质含量未能证明两种颗粒类型之间的任何差异。还进行了对衣壳和两种较小的外壳蛋白组分的尺寸，RNA含量和密度的研究。通过使用免疫分离和中和来研究五种不同病毒和MS-2的亚病毒颗粒的抗原相关性。衣壳和H和L病毒颗粒被证明是抗原相关的，而涂层蛋白质单体和二聚体显示出与较高分子量的颗粒无关。

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