首页> 外文期刊>Journal of Virology >Structure and function of herpesvirus genomes. I. comparison of five HSV-1 and two HSV-2 strains by cleavage their DNA with eco R I restriction endonuclease.
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Structure and function of herpesvirus genomes. I. comparison of five HSV-1 and two HSV-2 strains by cleavage their DNA with eco R I restriction endonuclease.

机译:Herpesvirus基因组的结构和功能。 I.用ECO R I限制性内切核酸酶对5 HSV-1和两种HSV-2菌株进行比较。

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摘要

The restriction endonuclease Eco R I cleaves HSV-1 and HSV-2 DNA into specific fragments that can be resolved by agarose gel electrophoresis. Comparison of HSV-1 strains KOS, 14-012, MP, F, and CI 101, and HSV-2 strains 333 and 186, suggests that the DNAs from type 1 strains are similar but not identical, and that the type 2 strains differ greatly from type 1 strains. The molecular lengths of the fragments have been determined by electron microscopy and can be used to calibrate gel electrophoretic analyses of DNA fragments.
机译:限制性内切核酸酶Eco R I将HSV-1和HSV-2 DNA切割成可通过琼脂糖凝胶电泳来解决的特定片段。 HSV-1菌株KOS,14-012,MP,F和CI101和HSV-2菌株333和186的比较表明,来自1型菌株的DNA是相似但不相同的,并且2型菌株不同从1型菌株中大大大。碎片的分子长已通过电子显微镜确定,可用于校准DNA片段的凝胶电泳分析。

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