首页> 外文期刊>Journal of Virology >Canavanine-mediated depletion of polyamine pools in Escherichia coli: effect of head morphogenesis and DNA synthesis.
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Canavanine-mediated depletion of polyamine pools in Escherichia coli: effect of head morphogenesis and DNA synthesis.

机译:Canavanine介导的大肠杆菌中的多胺池耗尽:头部形态发生和DNA合成的影响。

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We have found that L-canavanine inhibited the synthesis of polyamines in T4-infected Escherichia coli. These polyamines are known to be required for T4 DNA synthesis and may be involved in phage morphogenesis. The new data indicate that the inhibition of polyamine synthesis is not primarily responsible for the L-conavanine-mediated inhibition of DNA synthesis nor does it seem to be involved in the induction of lollipops. L-Canavanine does influence the relative amounts of putrescine and spermidine found in the phage particle, but it does not influence the amount of DNA phosphate neutralized by polyamines.
机译:我们发现L- Canavanine在T4感染的大肠杆菌中抑制了多胺的合成。已知这些多胺对于T4 DNA合成需要,并且可以参与噬菌体形态发生。新数据表明,多胺合成的抑制不是主要负责L- Conavanine介导的DNA合成的抑制,也没有似乎参与棒棒糖诱导。 L- Canavanine确实影响了噬菌体颗粒中发现的腐凝物和亚胺的相对量,但不会影响多胺中和的DNA磷酸的量。

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