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首页> 外文期刊>Journal of Virology >Selective Inhibition of Newcastle Disease Virus-Induced Glycoprotein Synthesis by d-Glucosamine Hydrochloride
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Selective Inhibition of Newcastle Disease Virus-Induced Glycoprotein Synthesis by d-Glucosamine Hydrochloride

机译:用D-葡萄糖胺盐酸盐的选择性抑制新城疫病毒诱导的糖蛋白合成

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d-Glucosamine selectively affected the synthesis of virus-induced glycoproteins in Newcastle disease virus-infected chick fibroblasts, but had no effect upon post-translational cleavage of the glycoprotein precursor for one of the two major glycoproteins of the mature virion. In response to glucosamine, at least one of the two virus-induced glycoproteins is formed in reduced quantity and the second is either not formed or has an electrophoretic mobility identical to that of another virus-induced protein.
机译:D-葡糖胺选择性地影响了新城疫病毒感染的鸡肉细胞中病毒诱导的病毒诱导的糖蛋白的合成,但对成熟病毒素的两个主要糖蛋白之一的糖蛋白前体的翻译后切割没有作用。响应于氨基葡萄糖,两种病毒诱导的糖蛋白中的至少一种在减少的量中形成,第二种病毒诱导的糖蛋白形成,第二种病毒诱导的蛋白质不形成或具有与另一种病毒诱导的蛋白质相同的电泳迁移率。

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