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首页> 外文期刊>Journal of Virology >Temperature-Sensitive Mutants of Murine Leukemia Virus IV. Further Physiological Characterization and Evidence for Genetic Recombination
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Temperature-Sensitive Mutants of Murine Leukemia Virus IV. Further Physiological Characterization and Evidence for Genetic Recombination

机译:鼠白血病病毒IV的温度敏感突变体。进一步的生理特征和遗传重组证据

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Several temperature-sensitive mutants of the Rauscher strain of murine leukemia virus representing three distinct physiological groups have been further characterized. Genetic recombination between different pairs of these mutants has been demonstrated. Several representative genetic recombinants were isolated and shown to replicate equally well at the permissive (31 C) and nonpermissive (38 C) temperatures and to have serological characteristics of the wild-type parental virus. Alternative models for the mechanisms involved in recombination between type C RNA viruses are discussed.
机译:还进一步表征了代表三种不同的生理基团的鼠白血病病毒的鼠李菌菌株的几种温度敏感突变体。已经证明了不同对这些突变体之间的遗传重组。分离出几种代表性遗传重组剂,并显示在允许(31℃)和非智能(38℃)温度下同样良好地复制并具有野生型父母病毒的血清学特征。讨论了C型RNA病毒之间涉及的重组机制的替代模型。

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