首页> 外文期刊>Journal of Virology >5'-terminal nucleotide sequences of the Rauscher leukemia virus and gibbon ape leukemia virus genomes exhibit a high degree of correspondence.
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5'-terminal nucleotide sequences of the Rauscher leukemia virus and gibbon ape leukemia virus genomes exhibit a high degree of correspondence.

机译:Rauscher白血病病毒和长臂猿白血病病毒基因组的5'-末端核苷酸序列表现出高度的对应程度。

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The 5'-terminal regions of gibbon ape leukemia virus-Hall's Island and Rauscher murine leukemia virus have been completely sequenced. The chain length for the 5'-terminal region of Rauscher murine leukemia virus is 140 nucleotides, and that for gibbon ape leukemia virus-Hall's Island is 144 nucleotides. An alignment of the sequences maximizing the number of ocrrespondences with the minimum introduction of gaps shows 81% nucleotide matches. From the complementary RNA, secondary structures of this region have been proposed. These data demonstrate the conservation of the 5'-terminal genetic sequences of these viruses and strongly reinforce the concept that viruses of murine origin and viruses of the gibbon ape leukemia virus-Simian sarcoma-associated virus group are closely related.
机译:已经完全测序了长臂猿白血病病毒大厅的5'-末端区域和Rauscher鼠白血病病毒。 Rauscher鼠白血病病毒的5'-末端区域的链长是140个核苷酸,对于长臂猿白血病病毒馆的岛是144个核苷酸。最大化序列的序列的对准与最小引入间隙的序列显示出81%的核苷酸匹配。从互补RNA,已经提出了该区域的二次结构。这些数据证明了这些病毒的5'-末端遗传序列的保护,强烈强化了小鼠猿白血病病毒 - 相关病毒组的鼠起源和病毒病毒的概念密切相关。

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