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Epstein-Barr virus DNA. X. Direct repeat within the internal direct repeat of Epstein-Barr virus DNA.

机译:Epstein-Barr病毒DNA。 X.直接重复Epstein-Barr病毒DNA的内部直接重复。

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摘要

The 3,360-base-pair internal direct repeat (IR) in Epstein-Barr virus DNA separates the short and long unique DNA domains. IR has a single BamHI site. The juncture between the short unique domain and IR has been mapped by restriction endonucleases and is less than 2,600 nucleotides before the BamHI site in IR. The junction between IR and the long unique domain has been sequenced and is approximately 650 nucleotides after the BamHI site in IR. Thus, relative to the start of IR at the juncture with the short unique domain, the last repeat is at least 90 base pairs short of being complete. There is homology between the 250-nucleotide fragments to the left and the right of the unique BamHI site in IR. A 35-base-pair sequence of the left fragment is directly repeated within the right fragment, once fully and once partially. The implications of these findings are discussed.
机译:Epstein-Barr病毒DNA中的3,360碱基对内部直接重复(IR)分离短而长的独特DNA结构域。 IR有一个Bamhi网站。短独特域和IR之间的关联已被限制性内切核酸酶映射,并且在IR的BamHI位点之前少于2,600个核苷酸。在IR中的BamHI位点后,IR和长唯一结构域之间的结率约为650个核苷酸。因此,相对于IR的开始在与短唯一域的接合处,最后重复是至少90个碱基对。在IR中独特BamHI位点的左侧和右侧的250核苷酸片段之间存在同源性。左片段的35碱基对序列直接在右片段内重复,一旦完全并且部分地重复。讨论了这些发现的含义。

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  • 来源
    《Journal of Virology》 |1981年第2期|共7页
  • 作者

    A Cheung; E Kieff;

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  • 收录信息 美国《科学引文索引》(SCI);
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