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首页> 外文期刊>Journal of Virology >Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.
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Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.

机译:鼠逆转录病毒限制基因FV-4和AkVR-1是单个基因座的等位基因。

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The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.
机译:两只鼠逆转录病毒限制基因,Fv-4和AkVR-1在其效果,分布,作用范围和表型中非常相似。 Akvr-1已被证明以各种逆转录病毒限制基因座独立分离,包括Fv-1,Fv-2,Ril-1和Ril-2。 FRG(FV-4R)X LCRR(AKVR-1R)杂种与AKR小鼠交配的等位感测试交叉未能产生任何雌激发后代。这些结果表明AkVR-1R和FV-4R是小鼠染色体12上单个基因座FV-4的等位基因。

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