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A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus.

机译:Epstein-Barr病毒高度剪接EBNA系列的推动者。

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摘要

A transcription start for the highly spliced EBNA group of RNAs in B95-8 cells has been identified in the short unique region of the virus genome. This promoter is used in many (but not all) human cell lines carrying Epstein-Barr virus, including a tightly latent human lymphoblastoid cell line. Another promoter for the EBNA RNAs was described previously in the internal repeat region of the virus genome. The existence of these alternative promoters may be important for differential control of EBNA gene expression.
机译:在病毒基因组的短独特区域中鉴定了B95-8细胞中高度剪接的EBNA组RNA的转录开始。该启动子用于许多(但不是全部)人细胞系携带Epstein-Barr病毒,包括紧密潜在的人淋巴细胞系细胞系。先前在病毒基因组的内部重复区域中描述了EBNA RNA的另一个启动子。这些替代促进剂的存在对于EBNA基因表达的差异控制可能是重要的。

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