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首页> 外文期刊>Water science & technology >Characterization of the inline virus removal performances in hollow fibre modules by a new tracer electrochemically detected
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Characterization of the inline virus removal performances in hollow fibre modules by a new tracer electrochemically detected

机译：通过电化学检测的新型示踪剂表征中空纤维组件中的在线病毒去除性能

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摘要

In a previous work, an innovative and patented method was presented, that is based on a new virus surrogate. This surrogate is an enzyme-labelled MS2 phage that is directly detectable and quantifiable by amperometry thanks to its induced enzymatic activity. In this work, this method was used to characterize the dynamics of virus removal in micromodules as a function of the membrane defect size and the transmembrane pressure (TMP). Experiments were performed at lab scale with an integer module and with modules made with the same fibres with calibrated holes (50, 100, 150 um) made in one of the module fibres with the laser method. Results showed first that the new method allowed diagnosing a 50 urn hole on the fibre of a micromodule. It was also demonstrated that, whatever the applied TMP, removal performances are all the more better that the defect size is smaller. Moreover, whatever the hole size, a TMP step rise from 1 to 1.5 bar during tracer filtration led to no significant change in the observed removal but improved the intrinsic removal performances.
机译：在以前的工作中，提出了一种创新的专利方法，该方法基于一种新的病毒替代物。该替代物是酶标记的MS2噬菌体，由于其诱导的酶促活性，可通过安培法直接检测和定量。在这项工作中，该方法用于表征微模块中病毒清除的动力学，该动力学是膜缺陷尺寸和跨膜压（TMP）的函数。实验是在实验室规模下用整数模和用相同的光纤制成的模块进行的，其中用激光方法在其中一根模光纤中制作了带有校准孔（50、100、150 um）的校准孔。结果首先表明，该新方法可以诊断微模块光纤上的50微米孔。还表明，无论采用何种TMP，缺陷尺寸越小，去除性能越好。此外，无论孔径大小如何，在示踪剂过滤过程中，TMP步长从1 bar增加到1.5 bar不会导致观察到的去除率发生明显变化，但改善了固有去除性能。

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  • 来源
    《Water science & technology》 |2013年第2期|507-514|共8页
  • 作者

    L. Soussan; M. Alquier; C. Guigui; S. Alfenore; S. Mathe; C. Cabassud;

  • 作者单位

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

    Universite de Toulouse,INSA, LISBP,135 Avenue de Rangueil,F-31077 Toulouse,France INRA,UMR792 Ingenierie des Systemes Biologiques et des Precedes,F-31400 Toulouse,France CNRS, UMR5504,F-31400 Toulouse,France;

  • 收录信息 美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    defect detection; dynamics of removal; membrane integrity; ms2 bacteriophage; virus removal; virus surrogate;

    机译：缺陷检测;清除动力学;膜完整性ms2噬菌体;病毒清除;病毒替代;

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