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首页> 外文期刊>World Journal of Acupuncture-moxibustion >EFFECTS OF HERBAL CAKE-SEPARATED MOXIBUSTION ON BLOOD LIPIDS, PLASMA THROMOXANE B2 AND 6 KETO-PROSTAGLANDIN F_(1α) CONTENTS IN THE RABBIT WITH HYPERLIPEMIA
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EFFECTS OF HERBAL CAKE-SEPARATED MOXIBUSTION ON BLOOD LIPIDS, PLASMA THROMOXANE B2 AND 6 KETO-PROSTAGLANDIN F_(1α) CONTENTS IN THE RABBIT WITH HYPERLIPEMIA

机译：高脂血症兔中药草隔灸对血脂，血浆中血栓素B2和6-酮-前列腺素F_（1α）含量的影响

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Objective: To observe effects of herbal cake-separated moxibustion on blood lipids, including total cholesterol (TCh), triglyceride (TG), high density lipoprotein-Ch (HDL-Ch), low density lipoprotein-Ch (LDL-Ch), apolipoprotein A (Apo A), apolipoprotein B (Apo B), and plasma thromboxane B2 (TXB2) and 6-keto-prostaglandin F_(1α)(6-keto-PGF_(1α)) contents and analyse its mechanism. Methods: The hyperlipemia rabbit model was established by breeding of high fat forage and injection of bovine seam albunin. They were treated respectively by direct moxibustion and herbal cake-separated moxibustion at Juque (CV 14), Tianshu (ST 25), Fenglong (ST 40), etc., once daily, continuously for 40 days. Blood TCh and TG contents were detected with enzymatic method, LDL-Ch and HDL-Ch with colorimetric method, Apo A and Apo B with electrophoretic method, and TXB2 and 6-keto-PGF_(1α)with radioimmunoassay. Results: Both the herbal cake-separated moxibustion and direct moxibustion could effectively decrease TCh, TG, LDL-Ch, Apo B and TXB2 contents and TXB2/6-keto-PGF_(1α), and increase HDL-CH and 6-keto-PGF_(1α) contents in the rabbit of hyperlipemia. Conclusion: 6-keto-PGF_(1α) and TXB2 are possibly involved in the mechanism of herbal cake-separated moxibustion decreasing blood lipids.
机译：目的：观察隔饼灸对总胆固醇（TCh），甘油三酸酯（TG），高密度脂蛋白-Ch（HDL-Ch），低密度脂蛋白-Ch（LDL-Ch），载脂蛋白等血脂的影响A（Apo A），载脂蛋白B（Apo B）和血浆血栓烷B2（TXB2）和6-酮-前列腺素F_（1α）（6-酮-PGF_（1α））的含量并分析其机理。方法：通过高脂饲喂和牛缝白蛋白注射液建立高脂血症兔模型。分别在Juque（CV 14），Tianshu（ST 25），Fenglong（ST 40）等处分别进行直接艾灸和草药蛋糕隔艾灸的治疗，每天一次，连续40天。酶法检测血TCh和TG含量，比色法检测LDL-Ch和HDL-Ch，电泳法检测Apo A和Apo B，放射免疫法检测TXB2和6-酮-PGF_（1α）。结果：草药饼隔灸和直接灸法均可有效降低TCh，TG，LDL-Ch，Apo B和TXB2含量以及TXB2 / 6-酮-PGF_（1α），并增加HDL-CH和6-酮-高脂血症兔的PGF_（1α）含量。结论：6-酮-PGF_（1α）和TXB2可能参与了艾草饼隔灸降低血脂的作用。

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