首页> 外文期刊>The Journal of Bone and Joint Surgery. British VolumecBritish Orthopaedic Association , Australian Orthopaedic Association , Canadian Orthopaedic Association . . . [et al] >Does cementing the femoral component increase the risk of peri-operative mortality for patients having replacement surgery for a fracture of the neck of femur?
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Does cementing the femoral component increase the risk of peri-operative mortality for patients having replacement surgery for a fracture of the neck of femur?

机译:对于进行股骨颈骨折置换手术的患者,固定股骨组件是否会增加围手术期死亡的风险?

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Concerns have been reported to the United KingdomNational Patient Safety Agency, warning that cementing the femoral componentduring hip replacement surgery for fracture of the proximal femurmay increase peri-operative mortality. The National Hip Fracture Database collects demographic and outcomedata about patients with a fracture of the proximal femur from over100 participating hospitals in the United Kingdom. We conducteda mixed effects logistic regression analysis of this dataset todetermine whether peri-operative mortality was increased in patientswho had undergone either hemiarthroplasty or total hip replacementusing a cemented femoral component. A total of 16?496 patients from129 hospitals were included in the analysis, which showed a smallbut significant adjusted survival benefit associated with cementing(odds ratio 0.83, 95% confidence interval 0.72 to 0.96). Other statisticallysignificant variables in predicting death at discharge, listed inorder of magnitude of effect, were gender, American Society of Anesthesiologistsgrade, age, walking accompanied outdoors and arthroplasty. Interactionterms between cementing and these other variables were sequentiallyadded to, but did not improve, the model. This study has not shown an increase in peri-operative mortalityas a result of cementing the femoral component in patients requiringhip replacement following fracture of the proximal femur.
机译:已经向英国国家患者安全局报告了担忧,警告说在髋关节置换手术中股骨近端骨折时将股骨组件固结可能会增加围手术期死亡率。国家髋部骨折数据库收集了来自英国100多家参与医院的股骨近端骨折患者的人口统计资料和结果数据。我们对该数据集进行了混合效应逻辑回归分析,以确定接受半髋置换或全髋置换术并使用股骨骨水泥假体的患者围手术期死亡率是否增加。该分析共纳入了来自129家医院的16?496例患者,结果显示与固井相关的生存率调整幅度很小但很明显(优势比0.83,95%置信区间0.72至0.96)。按效果大小顺序列出的其他在预测出院死亡时具有统计学意义的变量包括性别,美国麻醉医师学会等级,年龄,户外行走和人工关节置换。固井和其他变量之间的相互作用项被顺序添加到模型中,但并没有改善。这项研究没有显示由于在股骨近端骨折后需要髋关节置换术的患者中固定了股骨组件,因此没有增加围手术期死亡率。
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