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Fraud in clinical trials: Detecting it and preventing it

机译:临床试验中的欺诈:发现并预防

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摘要

Purpose: To point out that if one makes up or alters the data in a clinical trial it will leave a trail that a good statistician can follow. Summary: Much hangs on the results of clinical trials - for the patients, new and better treatments; for clinicians, prestige, promotion and pay. Thus the temptation to fabricate or falsify results or a trial is large. Most recorded such cases relate to ethical review and only less than 1% to research frauds. This short article does some loud thinking with a view to assist in fraud detection.
机译:目的:指出如果在临床试验中对数据进行补充或更改,将留下一个好的统计学家可以跟踪的线索。简介:临床试验的结果有很多悬念-对患者而言,新的更好的治疗方法;用于临床医生,声望,晋升和薪酬。因此,制造或伪造结果或进行审判的诱惑很大。记录的大多数此类案件都与道德审查有关,只有不到1%与研究欺诈有关。这篇简短的文章进行了一些大胆的思考,以帮助进行欺诈检测。

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