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EDITORIAL COMMENT

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Multiple previous authors have noted the association between high end filling detrusor pressures, detrusor overactivity, decreased bladder compliance/capacity, or high voiding pressures coexisting with high-grade reflux. Some have hypothesized that these patterns represent a developmental stage of normal bladder control and will resolve with time. This report, however, is unique in that all patients within the study had high-grade (greater than grade III-V) primary vesi-coureteral reflux and underwent video urodynamic studies while off all medications. This allowed the authors to determine the incidence of urodynamic abnormalities in this select patient population. The main "take home" points of this report are first that approximately 70% of patients with grade III or greater primary vesicoureteral reflux will have an end fill detrusor pressure of >40 cm, an overactive bladder, low bladder compliance, and/or a significantly reduced bladder capacity. Second, approximately 25% will have normal urodynamic patterns.
机译：先前的多位作者已经指出，高端充盈逼尿肌压力，逼尿肌过度活动，膀胱顺应性/容量下降或高排尿压力与高级别反流并存之间存在相关性。一些人假设这些模式代表了正常膀胱控制的发展阶段，并将随着时间的流逝而消退。然而，该报告的独特之处在于，研究中的所有患者均患有高级别（大于III-V级）原发性膀胱-膀胱反流，并且在不使用所有药物的情况下进行了视频尿动力学研究。这使作者能够确定所选患者群体中尿动力学异常的发生率。该报告的主要“重点”首先是，大约70％的III级或更高级别的原发性输尿管反流患者的末梢逼尿肌压力> 40 cm，膀胱过度活动，膀胱顺应性低和/或大大降低了膀胱容量。其次，大约25％的人会具有正常的尿动力模式。

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