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首页> 外文期刊>The American journal of hospice and palliative care >Palliation of heart failure.
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Palliation of heart failure.

机译：心力衰竭的姑息治疗。

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摘要

Heart failure is the major cause of morbidity and mortality in the United States. Stage D heart failure has a greater mortality rate than many cancers and has equivalent symptom burden and severity. There has been a paradigm shift in our understanding of the pathophysiology of heart failure. Progressive heart failure is associated with ventricular remodeling and a maladaptive neurohumoral response. Drug classes have evolved that curtail ventricular remodeling, and blunt neurohumoral responses reduce morbidity and mortality. Despite combination drug and device therapies, the management of Stage D heart failure includes palliation. Both cardiology and palliative specialists need to learn from one another in order to palliate these highly symptomatic patients. Such collaboration will enhance care and are the basis for well-conceived research trials.
机译：在美国，心力衰竭是发病率和死亡率的主要原因。 D期心力衰竭的死亡率高于许多癌症，并具有同等的症状负担和严重程度。我们对心力衰竭的病理生理学的理解发生了范式转变。进行性心力衰竭与心室重构和适应不良的神经体液反应有关。已经开发出可减少心室重塑和钝性神经体液反应降低发病率和死亡率的药物类别。尽管采用了药物和器械联合疗法，但D期心力衰竭的治疗仍包括缓解。心脏病专家和姑息治疗专家都需要互相学习，以缓解这些症状严重的患者。这种合作将提高护理水平，并且是构思良好的研究试验的基础。

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