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首页> 外文期刊>The European Journal of Neuroscience >Classical eyeblink conditioning in decerebrate guinea pigs.
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Classical eyeblink conditioning in decerebrate guinea pigs.

机译：去脑豚鼠的经典眨眼条件。

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摘要

A decerebrate guinea pig preparation was used to test the hypothesis that brainstem-cerebellar circuitry is sufficient for classical delay eyeblink conditioning. Delay conditioning was carried out using a tone conditioned stimulus (CS) paired with a co-terminating, periorbital shock unconditioned stimulus (US). Decerebrate animals readily acquired the conditioned response (CR), while pseudoconditioning yielded no signs of learning. When a longer tone CS was used, the learning became slower. These CRs were adaptive and appropriately timed relative to the US. Subsequent CS-alone trials caused extinction of the CR. These characteristics of the eyeblink conditioning were similar to those reported previously in various species, suggesting that the cerebellum and brainstem are sufficient for this type of learning.
机译：使用无脑豚鼠制剂测试以下假设：脑干-小脑回路足以进行经典的延迟眨眼调节。延迟条件调节是通过声调条件刺激（CS）与共终止的眶周休克非条件刺激（US）配对进行的。无脑动物容易获得条件反应（CR），而假条件没有任何学习迹象。使用较长的CS时，学习会变慢。这些CR具有自适应性，并且相对于美国具有适当的时间。随后的仅CS试验导致CR消失。眨眼条件调节的这些特征与先前在各种物种中报道的特征相似，表明小脑和脑干足以进行此类学习。

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