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Treatment of Hypertension Among African Americans: The Jackson Heart Study

机译:非裔美国人高血压的治疗:杰克逊心脏研究

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Hypertension treatment regimens used by African American adults in the Jackson Heart Study were evaluated at the first two clinical examinations (2415 treated hypertensive persons at examination I [exam I], 2000-2004; 2577 at examination II [exam II], 2005-2008). Blood pressure (BP) was below 140/90 mm Hg for 66% and 70% of treated participants at exam I and exam II, respectively. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure treatment targets were met for 56% and 61% at exam I and exam II, respectively. Persons with diabetes or chronic kidney disease were less likely to have BP at target, as were men compared with women. Thiazide diuretics were the most commonly used antihypertensive medication, and persons taking a thiazide were more likely to have their BP controlled than persons not taking them; thiazides were used significantly less among men than women. Although calcium channel blockers are often considered to be effective monotherapy for African Americans, persons using calcium channel blocker monotherapy were significantly less likely to be at target BP than persons using thiazide monotherapy.
机译:在前两次临床检查中评估了非裔美国成年人在杰克逊心脏研究中使用的高血压治疗方案(2000-2004年,在检查I [检查I]中检查了2415名高血压患者,在检查II [检查II]中检查了2577名高血压患者,2005-2008 )。在考试I和考试II中,分别有66%和70%的被治疗参与者的血压(BP)低于140/90 mm Hg。全国预防,检测,评估和治疗高血压联合委员会的第七次报告分别在考试I和考试II中分别达到了56%和61%。与男性相比,糖尿病或慢性肾脏疾病患者的血压降低的可能性较小。噻嗪类利尿剂是最常用的降压药,与不服用噻嗪类药物的人相比,服用噻嗪类药物的人更容易控制血压。男性中噻嗪类的使用明显少于女性。尽管通常认为钙通道阻滞剂对非裔美国人是有效的单一疗法,但是使用钙通道阻滞剂单一疗法的患者与使用噻嗪类单一疗法的患者相比,达到目标BP的可能性大大降低。

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