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首页> 外文期刊>The journal of clinical psychiatry >Impact of bipolar disorder on a U.S. community sample.
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Impact of bipolar disorder on a U.S. community sample.

机译：躁郁症对美国社区样本的影响。

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BACKGROUND: Bipolar disorder is a chronic psychiatric illness characterized by depression and at least 1 manic or hypomanic episode during the lifetime of the illness. Bipolar symptoms have been associated with significant functional impairment. We conducted a study to determine the psychosocial impact of bipolar disorder in a U.S. community sample. METHOD: 3059 subjects were selected from a large epidemiologic study of bipolar prevalence that used the Mood Disorder Questionnaire (MDQ) to screen for bipolar I and II disorder. Subjects were surveyed from April 24, 2001, to August 6, 2001, using the Sheehan Disability Scale and the Social Adjustment Scale-Self Report. Comorbid disease data were also collected. RESULTS: Of the 3059 subjects surveyed, 2450 (80%) returned completed surveys: 1167 (48%) subjects screened positive for bipolar disorder based on MDQ scores; 1283 (52%) screened negative. MDQ-positive subjects reported significantly (p <.0001) more difficulties with work-related performance, social/leisure activities, and social/family interactions compared with MDQ-negative subjects. Younger subjects, aged 18 to 34 years, reported significantly (p =.003) more symptom days than did older MDQ-positive subjects. MDQ-positive women reported more disruption in social and family life, while MDQ-positive men reported being jailed, arrested, and convicted for crimes. Anxiety (30% vs. 6%), panic attacks (18% vs. 4%), migraine (24% vs. 11%), asthma (17% vs. 10%), and allergies (42% vs. 29%) were significantly (p <.05) more common in MDQ-positive versus MDQ-negative subjects. CONCLUSION: Bipolar disorder, as identified in a community sample using the Mood Disorder Questionnaire, was significantly associated with negative impact on the performance of work-related, leisure, and interpersonal activities.
机译：背景：双相情感障碍是一种慢性精神疾病，其特征是在疾病的一生中抑郁症和至少1次躁狂或躁狂发作。躁郁症与严重的功能障碍有关。我们进行了一项研究，以确定美国社区样本中躁郁症的心理社会影响。方法：从一项双相流行的大型流行病学研究中选择了3059名受试者，该研究使用情绪障碍问卷（MDQ）筛选了I和II型双相情感障碍。从2001年4月24日至2001年8月6日，使用希恩残疾量表和社会适应量表-自我调查报告对受试者进行了调查。还收集了合并症疾病数据。结果：在接受调查的3059名受试者中，有2450名（80％）返回完成的调查：1167名（48％）受试者根据MDQ分数筛查出双相情感障碍阳性。 1283（52％）筛选为阴性。与MDQ阴性受试者相比，MDQ阳性受试者报告的与工作相关的绩效，社交/休闲活动以及社交/家庭互动方面的困难显着（p <.0001）。年龄在18至34岁之间的年轻受试者报告的症状天数比老年MDQ阳性受试者多（p = .003）。 MDQ阳性的妇女报告称其社交和家庭生活受到更多破坏，而MDQ阳性的男性报告称因犯罪而被监禁，逮捕和定罪。焦虑症（30％对6％），惊恐发作（18％对4％），偏头痛（24％对11％），哮喘（17％对10％）和过敏症（42％对29％） ）在MDQ阳性患者中明显比在MDQ阴性患者中更常见（p <.05）。结论：使用情绪障碍问卷在社区样本中确定的躁郁症与对工作相关，休闲和人际交往活动的负面影响显着相关。

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