Adjunctive Brexpiprazole 1 and 3 mg for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Phase 3, Randomized, Double-Blind Study

Thase Michael E.; Youakim James M.; Skuban Aleksandar; Hobart Mary; Zhang Peter; McQuade Robert D.; Nyilas Margaretta; Carson William H.; Sanchez Raymond; Eriksson Hans

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Adjunctive Brexpiprazole 1 and 3 mg for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Phase 3, Randomized, Double-Blind Study

机译：对抗抑郁药反应不足后出现严重抑郁障碍的患者联合使用Brexpiprazole 1和3 mg：3期随机双盲研究

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Objective: To evaluate efficacy, safety, and tolerability of brexpiprazole adjunctive to antidepressant treatments (ADTs) in patients with major depressive disorder (as defined by DSM-IV-TR criteria) with inadequate response to ADTs.

机译：目的：评估在抗抑郁药不良反应（DSM-IV-TR标准定义）的重度抑郁症患者中，抗抑郁药（ADT）辅助使用的brexpiprazole的疗效，安全性和耐受性。

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来源
《The journal of clinical psychiatry》 |2015年第9期|共17页
作者
Thase Michael E.; Youakim James M.; Skuban Aleksandar; Hobart Mary; Zhang Peter; McQuade Robert D.; Nyilas Margaretta; Carson William H.; Sanchez Raymond; Eriksson Hans;
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正文语种 eng
中图分类精神病学;
关键词
Antidepressants; Depression;

机译：抗抑郁药;抑郁症;

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1. Adjunctive Brexpiprazole 1 and 3 mg for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Phase 3, Randomized, Double-Blind Study [J] . Aleksandar Skuban, Hans Eriksson, James M. Youakim, Primary care companion to the journal of clinical psychiatry . 2015,第9期

机译：对抗抑郁药反应不足后出现严重抑郁障碍的患者联合使用Brexpiprazole 1和3 mg：3期随机双盲研究
2. Efficacy and Safety of Adjunctive Brexpiprazole 2 mg in Major Depressive Disorder: A Phase 3, Randomized, Placebo-Controlled Study in Patients With Inadequate Response to Antidepressants [J] . Aleksandar Skuban, Carole Augustine, James M. Youakim, Primary care companion to the journal of clinical psychiatry . 2015,第9期

机译：辅助性布雷哌拉唑2 mg在严重抑郁症中的疗效和安全性：对抗抑郁药反应不足的患者的一项3期，随机，安慰剂对照研究
3. Efficacy and Safety of Adjunctive Brexpiprazole 2 mg in Major Depressive Disorder: A Phase 3, Randomized, Placebo-Controlled Study in Patients With Inadequate Response to Antidepressants [J] . Thase Michael E., Youakim James M., Skuban Aleksandar, The journal of clinical psychiatry . 2015,第9期

机译：辅助性布雷哌拉唑2 mg在严重抑郁症中的疗效和安全性：对抗抑郁药反应不足的患者的一项3期，随机，安慰剂对照研究
4. Patients with Major Depressive Disorder Alters Dorsal Medial Prefrontal Cortex Response to Anticipation with Different Saliences [C] . Bin Zhang, Jijun Wang International conference on brain informatics . 2017

机译：患有严重抑郁症的患者改变了背侧内侧前额叶皮层对不同显着性预期的反应
5. A Randomized, Double-Blind, Placebo-Controlled Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder. [D] . Cha, Danielle Soh-Young. 2016

机译：一项随机，双盲，安慰剂对照的交叉试验评估了鼻内胰岛素对难治性重度抑郁症患者认知和情绪加工的影响。
6. Effects of Adjunctive Aripiprazole on Sexual Functioning in Patients With Major Depressive Disorder and an Inadequate Response to Standard Antidepressant Monotherapy: A Post Hoc Analysis of 3 Randomized Double-Blind Placebo-Controlled Studies [O] . Maurizio Fava, Christina M. Dording, Ross A. Baker, 2011

机译：辅助性阿立哌唑对重度抑郁症患者性功能的影响以及对标准抗抑郁单一疗法的反应不足：3项随机双盲安慰剂对照研究的事后分析
7. Effects of Adjunctive Aripiprazole on Sexual Functioning in Patients With Major Depressive Disorder and an Inadequate Response to Standard Antidepressant Monotherapy: A Post Hoc Analysis of 3 Randomized, Double-Blind, Placebo-Controlled Studies [O] . Fava, Maurizio, Dording, Christina M., Baker, Ross A., 2011

机译：辅助性阿立哌唑对重度抑郁症患者的性功能及对标准抗抑郁单一疗法反应不足的影响：3项随机，双盲，安慰剂对照研究的事后分析

Adjunctive Brexpiprazole 1 and 3 mg for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Phase 3, Randomized, Double-Blind Study

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