Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Bipolar Disorder: A Review of Biomarker and Treatment Studies

Saunders Erika F. H.; Ramsden Christopher E.; Sherazy Mostafa S.; Gelenberg Alan J.; Davis John M.; Rapoport Stanley I.

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Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Bipolar Disorder: A Review of Biomarker and Treatment Studies

机译：双相情感障碍中的Omega-3和Omega-6多不饱和脂肪酸：生物标志物和治疗研究的回顾。

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Objective: There is growing evidence that inflammation is an important mediator of pathophysiology in bipolar disorder. The omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acid (PUFA) metabolic pathways participate in several inflammatory processes and have been linked through epidemiologic and clinical studies to bipolar disorder and its response to treatment. We review the data on PUFAs as biomarkers in bipolar disorder and n-3 PUFA used as treatment for bipolar disorder.

机译：目的：越来越多的证据表明炎症是双相情感障碍的重要病理生理介质。 omega-3（n-3）和omega-6（n-6）多不饱和脂肪酸（PUFA）代谢途径参与多种炎症过程，并已通过流行病学和临床研究与双相情感障碍及其对治疗的反应相关。我们回顾了有关双相情感障碍中作为生物标志物的PUFAs和n-3 PUFA用作双相情感障碍治疗的数据。

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《The journal of clinical psychiatry》 |2016年第10期|共8页
作者
Saunders Erika F. H.; Ramsden Christopher E.; Sherazy Mostafa S.; Gelenberg Alan J.; Davis John M.; Rapoport Stanley I.;
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正文语种 eng
中图分类精神病学;
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Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Bipolar Disorder: A Review of Biomarker and Treatment Studies

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