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首页> 外文期刊>The journal of sexual medicine >The Relationship between Lifelong Premature Ejaculation and Monosymptomatic Enuresis
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The Relationship between Lifelong Premature Ejaculation and Monosymptomatic Enuresis

机译：终生早泄与单症状性遗尿的关系

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Introduction. Although both biological and psychological factors are important in the etiologies, the underlying physiopathologies of lifelong premature ejaculation (PE) and monosymptomatic enuresis (ME) are not completely understood. Aim. The aim of this study is to evaluate the prevalence of ME in men diagnosed with lifelong PE and relationships of these two conditions. Methods. Between December 2008 and November 2009, we designed a prospective randomized study in 51 patients who had presented with lifelong PE and in age-matched 106 healthy control cases without PE. If the patient declared that he ejaculated less than 1 minute more than half of his intercourse attempts, he was enrolled in the study. Main Outcome Measures. All subjects included in this study underwent general and urological physical examinations and were asked about their history of ME. The frequency of enuresis was graded using the following criteria: (i) 1-2 times/week as infrequent; (ii) 3-5 times/week as moderate; and (iii) 6-7 times/week as severe. Only patients with primary ME were evaluated. Results. Of the 51 premature ejaculator men, 19 (37.2%) had a history of ME. Among these 19 men, five (26.3%) had severe, six (31.6%) had moderate, and eight (42.1%) had infrequent enuresis. Of the 106 control cases, 16 (15.1%) had a history of ME and of these 16 patients, three (18.7%) had severe, five (31.2%) had moderate, and eight (50%) had infrequent enuresis. Compared with control population (15.1%), the prevalence of ME in the premature ejaculators (37.2%) was more than twofold higher (P< 0.005). Conclusion. We have found a significant increase in ME prevalence in lifelong premature ejaculators. A common deficiency of inhibitory signal processing in the central nervous system may underlie both inability to inhibit the ejaculation and micturition in these patients or genetic predisposition may play a significant role. Further prospective studies are needed to explain the relationship between lif...
机译：介绍。尽管生物学和心理因素在病因中均很重要，但终生早泄（PE）和单症状性遗尿（ME）的潜在生理病理学尚未完全了解。目标。这项研究的目的是评估诊断为终身PE的男性中ME的患病率以及这两种情况之间的关系。方法。在2008年12月至2009年11月之间，我们设计了一项前瞻性随机研究，研究对象为51例终身患有PE的患者，以及年龄匹配的106例无PE的健康对照组。如果患者宣布自己的性交尝试次数超过一半，则射精时间少于1分钟，则他被纳入研究。主要观察指标。纳入本研究的所有受试者均接受了常规和泌尿科的体格检查，并被询问其ME病史。使用以下标准对遗尿频率进行分级：（i）每周1-2次（不频繁）; （ii）每周3-5次为中度; （iii）每周重度6-7次。仅对原发性ME患者进行了评估。结果。在51名早泄男性中，有19名（37.2％）患有ME。在这19名男性中，有5名（26.3％）为重度，有6名（31.6％）为中度，有8名（42.1％）为不常见的遗尿。在106例对照病例中，有16例（15.1％）具有ME病史，在这16例患者中，三例（18.7％）为重度，五例（31.2％）为中度，八例（50％）不常遗尿。与对照组相比（15.1％），早泄者中ME的患病率（37.2％）高出两倍以上（P <0.005）。结论。我们发现终身早泄者的ME患病率显着增加。中枢神经系统抑制信号处理的普遍缺陷可能是无法抑制这些患者的射精和排尿，或者遗传因素可能起重要作用。需要进一步的前瞻性研究来解释生活水平之间的关系。

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