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Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men

机译:低强度和高强度中等强度运动对肥胖男性性功能和睾丸激素的影响

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Introduction: Obesity and inactivity are associated with erectile dysfunction and hypogonadism. Aim: To compare the effects of low volume (LV) and high volume (HV) of moderate-intensity exercise on sexual function, testosterone, lower urinary tract symptoms (LUTS), endothelial function, and quality of life (QoL) in obese men. Main Outcome Measures: Weight, waist circumference (WC), body composition, International Index of Erectile Function 5-item (IIEF-5), International Prostate Symptom Scale (IPSS) (for LUTS), and 36-item Short Form Survey version 2 Instrument (SF-36) (for QoL) scores, plasma testosterone, sex-hormone binding globulin, glucose, insulin and lipids, and endothelial function (by Reactive Hyperaemia Index [RHI] using finger plethysmography) were measured at baseline and 24 weeks. Methods: Ninety abdominally obese (body mass index27.5kg/m2, WC90cm), sedentary (exercise ~80 minutes/week) Asian men (mean age 43.6 years, range 30-60) were prescribed a diet to reduce daily intake by ~400kcal below calculated requirement and randomized to perform moderate-intensity exercise of LV (150 minutes/week) or HV (200-300 minutes/week) (n=45 each) for 24 weeks. Seventy-five men (83.3%) completed the study. Results: Weekly exercise volume was significantly greater in the HV (236±9 minutes) than the LV (105±9 minutes) group. The HV group had significantly greater increases in IIEF-5 score (2.6±0.5 points) and testosterone (2.06±0.46nmol/L) and reductions in weight (-5.9±0.7kg, -6.2%), WC (-4.9±0.8cm, -4.9%), and fat mass (-4.7±1.0kg, -14.5%) than the LV group (-2.9±0.7kg, -3.0%; -2.7±0.7cm, -2.5%; -1.1±0.8kg, -3.2%; 0.79±0.46nmol/L; and 1.8±0.5 points). Improvements in IPSS and SF-36 scores, and RHI, were similar. Conclusions: Moderate-intensity HV aerobic exercise200 minutes/week produces greater improvements in sexual function, testosterone, weight, WC, and fat mass than smaller exercise volume.
机译:简介:肥胖和不活动与勃起功能障碍和性腺功能减退有关。目的:比较中等强度运动的低容量(LV)和高容量(HV)对肥胖男性性功能,睾丸激素,下尿路症状(LUTS),内皮功能和生活质量(QoL)的影响。主要观察指标:体重,腰围(WC),身体成分,国际勃起功能指数5项(IIEF-5),国际前列腺症状量表(IPSS)(用于LUTS)和36项简短调查表2在基线和24周时测量了器械(SF-36)(针对QoL)的得分,血浆睾丸激素,性激素结合球蛋白,葡萄糖,胰岛素和脂质以及内皮功能(通过使用手指体积描记法的反应性充血指数[RHI])。方法:对90名腹部肥胖(体重指数> 27.5kg / m2,WC> 90cm),久坐(运动〜80分钟/周)的亚洲男性(平均年龄43.6岁,范围30-60)进行处方饮食以减少每日摄入量低于计算的需求量约400kcal,并随机进行LV(<150分钟/周)或HV(200-300分钟/周)(每个n = 45)的中等强度运动,持续24周。七十五名男性(83.3%)完成了研究。结果:HV(236±9分钟)组的每周运动量显着大于LV(105±9分钟)组的运动量。 HV组IIEF-5得分(2.6±0.5分)和睾丸激素(2.06±0.46nmol / L)显着增加,体重减轻(-5.9±0.7kg,-6.2%),WC(-4.9±0.8)厘米,-4.9%)和脂肪量(-4.7±1.0kg,-14.5%)比LV组(-2.9±0.7kg,-3.0%; -2.7±0.7cm,-2.5%; -1.1±0.8 kg,-3.2%; 0.79±0.46nmol / L;和1.8±0.5点)。 IPSS和SF-36分数以及RHI的改善相似。结论:中等强度的HV有氧运动> 200分钟/周,与较小的运动量相比,对性功能,睾丸激素,体重,WC和脂肪量的改善更大。

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