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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Executive function and gait in older adults with cognitive impairment.
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Executive function and gait in older adults with cognitive impairment.

机译：认知障碍老年人的执行功能和步态。

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BACKGROUND: Cognitive impairment has been shown to predict falls risk in older adults. The ability to step accurately is necessary to safely traverse challenging terrain conditions such as uneven or slippery surfaces. However, it is unclear how well persons with cognitive impairment can step accurately to avoid such hazards and what specific aspects of cognition predict stepping ability in different patient populations. METHODS: Healthy older adults (NC), patients with Mild Cognitive Impairment with only memory impairment (MCI-EF) or memory and executive function impairments (MCI+EF) and early Alzheimer's patients (AD) were timed as they performed a stepping accuracy test with increasing cognitive demand (Walking Trail-Making Test; W-TMT), which required stepping on instrumented targets with either increasing sequential numbers (W-TMT A) or alternating sequential numbers and letters (W-TMT B). RESULTS: After accounting for age and baseline walking speed, the AD and MCI+EF groups were significantly slower than the NC and MCI-EF groups on the task with the highest cognitive demand, W-TMT B (interaction effect F = 6.781, p <.0001). No group differences were noted on the W-TMT A task that was less cognitively demanding. Neuropsychological measures of executive functioning were associated with slower W-TMT B performance, whereas memory, visual attention and visual spatial skills were not (adjusted R(2) = 0.42). CONCLUSIONS: Executive function is important for stepping performance, particularly under more complex environmental conditions.
机译：背景：认知障碍已被证明可以预测老年人跌倒的风险。为了安全地穿越具有挑战性的地形条件（例如不平坦或光滑的表面），必须具有准确踏步的能力。然而，尚不清楚认知障碍者能如何准确地迈步避免此类危险，以及认知的哪些具体方面预测了不同患者人群的迈步能力。方法：对健康的老年人（NC），仅具有记忆障碍（MCI-EF）或记忆和执行功能障碍（MCI + EF）的轻度认知障碍患者以及早期阿尔茨海默氏病（AD）进行计时准确性测试随着认知需求的增加（步履式测验; W-TMT），这要求踩踏有序列号（W-TMT A）或交替的序列号和字母（W-TMT B）增加的仪器目标。结果：在考虑了年龄和基线行走速度之后，AD和MCI + EF组在认知需求最高的任务W-TMT B上显着低于NC和MCI-EF组（交互作用F = 6.781，p <.0001）。在W-TMT A任务上，没有注意到认知上要求较低的小组差异。执行功能的神经心理学测量与较慢的W-TMT B性能相关，而记忆，视觉注意力和视觉空间技能则不相关（调整后的R（2）= 0.42）。结论：执行功能对于步进性能很重要，特别是在更复杂的环境条件下。

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