Oxybutynin in detrusor overactivity.

Diokno A; Ingber M

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Oxybutynin in detrusor overactivity.

机译：奥昔布宁在逼尿肌过度活动中。

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Oxybutynin has been used for the management of detrusor overactivity for over 30 years and has withstood medical scrutiny and the test of time throughout the world. Although several agents in the class of bladder relaxants have only recently been studied, oxybutynin's effectiveness in reducing urinary frequency and urge urinary incontinence is unquestioned in the medical literature. Oxybutynin is extremely safe and effective in almost every population including children, the elderly, and those who have neurogenic bladder. With more preparations available and more dosing flexibility than any other anticholinergic medication on the market, oxybutynin remains the "gold standard" for first-line therapy for patients who have detrusor overactivity.

机译：奥昔布宁用于治疗逼尿肌过度活跃已有30多年的历史，在世界范围内经受了医学检查和时间的考验。尽管直到最近才研究了膀胱松弛剂类中的几种药物，但是奥昔布宁在降低尿频和催促尿失禁方面的有效性在医学文献中没有受到质疑。奥昔布宁在几乎所有人群中都非常安全和有效，包括儿童，老人和患有神经源性膀胱癌的人群。与市场上任何其他抗胆碱能药物相比，可用的制剂更多，给药灵活度更高，奥昔布宁仍然是逼尿肌过度活动患者一线治疗的“金标准”。

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来源
《The Urologic clinics of North America》 |2006年第4期|共8页
作者
Diokno A; Ingber M;
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原文格式 PDF
正文语种 eng
中图分类临床医学;
关键词
oxybutynin; Gold preparation; Therapeutic procedure; Urinary Incontinence; 尿失禁;

机译：奥昔布宁;金制剂;治疗程序;尿失禁;尿失禁;

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专利

1. Intravesical oxybutynin protects the vesical wall against functional and smooth muscle changes in rabbits with detrusor overactivity. [J] . Polido Junior A, Costa JM, Munhoz T, International urogynecology journal and pelvic floor dysfunction . 2010,第12期

机译：膀胱内奥昔布宁可保护膀胱壁免受逼尿肌过度活动的兔子的功能性和平滑肌变化。
2. Protective action of intravesical oxybutynin on bladder ultrastructure in rabbits with detrusor overactivity. [J] . Yamamoto H, Kawano PR, Balasteghin KT, International urogynecology journal and pelvic floor dysfunction . 2009,第2期

机译：膀胱内奥昔布宁对逼尿肌过度活跃的家兔膀胱超微结构的保护作用。
3. Intravesical instillation of human urine after oral administration of trospium, tolterodine and oxybutynin in a rat model of detrusor overactivity. [J] . Kim Y, Yoshimura N, Masuda H, BJU international . 2006,第2期

机译：在逼尿肌过度活跃的大鼠模型中，口服给予Trospium，tolterodine和oxybutynin后，膀胱内滴注人尿。
4. Use of Electrical Stimulation of the Posterior Tibial Nerve in Patients with Bladder Hyperactivity as a Substitute for Pharmacological Therapy based on Solifenacin Succinate and Oxybutynin Hyloridrate [C] . Fabiana Bianchi Perez, Jose Natal de Souza, Nathalia Cristina Rosa, International Conference on Biomedical Electronics and Devices . 2016

机译：基于Solifencin琥珀酸盐和oxybutynin Hyloridrate的药理学治疗患者膀胱多动患者后胫骨神经电刺激的使用
5. A case-control study exploring the relationships between risk factors of detrusor underactivity and bladder outlet obstruction and incomplete bladder emptying in community-dwelling women aged 65 or older who have overactive bladder symptoms [D] . Park, Jeongok. 2011

机译：病例对照研究探讨了逼尿肌活动不足和膀胱出口梗阻的危险因素与膀胱过度活跃症的65岁以上社区居民妇女膀胱排空不完全之间的关系
6. Intradetrusor onabotulinumtoxinA injections are significantly more efficacious than oral oxybutynin for treatment of neurogenic detrusor overactivity: results of a randomized controlled 24-week trial [O] . Rúiter Silva Ferreira, Carlos Arturo Levi D’Ancona, Matthias Oelke, 2018

机译：Intradetrusor上的肉毒杆菌毒素A注射比奥昔布宁口服治疗神经源性逼尿肌过度活动的疗效显着：一项随机对照24周试验的结果
7. Hiperatividade do detrusor: comparação entre oxibutinina, eletroestimulação funcional do assoalho pélvico e exercícios perineais. Estudo randomizado Detrusor overactivity: comparative study among oxybutynin, functional electrostimulation and pelvic floor training. A randomized clinical trial [O] . Raquel Martins Arruda, Gabriela Olbrich de Sousa, Rodrigo de Aquino Castro, 2007

机译：逼尿肌过度活跃：奥昔布宁，盆底功能性电刺激和会阴运动之间的比较。随机研究逼尿肌过度活动：奥昔布宁，功能性电刺激和骨盆底训练的比较研究。一项随机临床试验
8. Double Blind, Randomized Study of Safety and Efficacy of OnabotulinumtoxinA (OnaBoNT A) versus Oral Oxybutynin in SCI Patients with NDO (11 09 10 04). [R] . Smith, C. P. 2017

机译：双盲，随机研究Onabotulinumtoxina（OnaBoNT a）与口服奥昔布宁在NDO患者中的安全性和有效性（11 09 10 04）。

Oxybutynin in detrusor overactivity.

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