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首页> 外文期刊>Trends in Neurosciences >Spine motility: a means towards an end?
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Spine motility: a means towards an end?

机译:脊柱运动性:达到目的的手段吗?

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摘要

From the first glimpse of moving spines half a decade ago, the prevailing view has been that spine contortions and wiggling, especially during development, maximize encounters with presynaptic growth cones or synaptic boutons. Other new evidence has revealed that spines continue to be motile even after they settle on a presynaptic partner and form a synapse. We present the evidence for each view, and discuss how spines with synapses could move relative to their apparently stable presynaptic partners. Thus, spine motility might not simply be a means towards an end of synapse formation, but could continue, albeit at a lower rate, during synapse turnover after development ends.
机译:从十年前的活动脊椎第一眼瞥见,普遍的观点是,脊柱扭曲和摆动(尤其是在发育过程中)使与突触前生长锥或突触钮扣的接触最大化。其他新证据表明,即使棘突定居于突触前伴侣并形成突触后,脊突仍能活动。我们提供每种观点的证据,并讨论带有突触的刺如何相对于其表面上稳定的突触前伴侣移动。因此,脊柱活动力可能不仅是结束突触形成的一种手段,而且在发育结束后的突触周转过程中可能会以较低的速度持续下去。

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