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首页> 外文期刊>The International journal of pharmacy practice >What factors affect medication-storage practice among patients on methadone maintenance treatment?
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What factors affect medication-storage practice among patients on methadone maintenance treatment?

机译：哪些因素会影响美沙酮维持治疗患者的药物存储实践？

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Objectives Medication storage in patients' homes is an important safety issue. Safe storage of methadone oral solution is of particular concern. Previous studies have suggested that only about half of patients store methadone appropriately. The aims of this study were to describe medication-storage practice in a sample of patients receiving methadone maintenance treatment (MMT), and to identify factors associated with safe storage. Methods The setting was a primary health care centre in Edinburgh, Scotland. One hundred and four consecutive patients on MMT completed a self-administered questionnaire covering medication-storage practice, together with clinical and demographic variables. Storage of medication was classified as 'acceptable' if medication was out of sight and out of reach of children, and 'optimal' if it was also kept in a secure container.Key findings Percentages (95% confidence intervals) for acceptable and optimal storage were as follows: methadone 80% (71-86%) and 33% (24-42%); other prescribed medication 69% (59-78%) and 27% (19-37%); purchased medication 64% (50-76%) and 28% (17^-2%). Safe storage of methadone was more common in patients taking higher doses of methadone (P = 0.004 for acceptable storage, and P = 0.012 for optimal storage), and in those with children in the house (P = 0.007 and 0.061). Safe storage of prescribed and purchased medication was strongly associated with safe storage of methadone (P < 0.01 in both cases).Conclusions Medication-storage practice was better than in previous surveys of patients on MMT. This may reflect the high profile given to safety issues for children of drug-using parents in Scotland, as well as local initiatives. Some aspects of prescribing and dispensing practice could be improved further.
机译：目的在患者家中存放药物是一个重要的安全问题。美沙酮口服溶液的安全储存尤为重要。先前的研究表明，只有大约一半的患者适当地存储了美沙酮。这项研究的目的是描述接受美沙酮维持治疗（MMT）的患者样本中的药物存储实践，并确定与安全存储相关的因素。方法该机构是苏格兰爱丁堡的一家初级卫生保健中心。连续接受MMT治疗的104位患者完成了一份自我管理的调查问卷，内容涉及药物存储的做法以及临床和人口统计学变量。如果药物在儿童的视线范围之外或儿童无法触及的地方，则将其存储为``可接受的'';如果也将其保存在安全的容器中，则将其分类为``最佳''。分别为：美沙酮80％（71-86％）和33％（24-42％）;其他处方药69％（59-78％）和27％（19-37％）;购买药物的比例为64％（50-76％）和28％（17 ^ -2％）。在服用高剂量美沙酮的患者中，安全储存美沙酮更为常见（可接受的储存量为P = 0.004，最佳储存的情况下P = 0.012），以及有孩子的家庭（P = 0.007和0.061）。安全存储处方药和购买的药物与美沙酮的安全存储密切相关（两种情况下，P <0.01）。结论药物存储实践优于以前接受MMT的患者调查。这可能反映出苏格兰对吸毒父母子女的安全问题以及地方倡议的高度重视。处方和配药实践的某些方面可以进一步改善。

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