Percutaneous Intervention for Mitral Regurgitation

Sarraf Mohammad; Feldman Ted

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Percutaneous Intervention for Mitral Regurgitation

机译：经皮介入治疗二尖瓣反流

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摘要

Percutaneous treatment of mitral regurgitation (MR) is a promising alternative for patients with functional MR (FMR) who are not appropriate for surgery and are not responding to optimal medical therapy and cardiac resynchronization therapy. Unlike degenerative MR, where repair therapy is clearly preferred, the optimal approach for FMR has not been defined. Challenges for novel mitral repair devices are to demonstrate safety and superior efficacy to medical management in higher risk patients. Transcatheter mitral valve replacement is emerging as a feasible therapy, but requires significant additional clinical trials to define its place in treating heart failure related to MR.

机译：对于不适合手术且对最佳药物治疗和心脏再同步治疗无反应的功能性MR（FMR）患者，经皮二尖瓣关闭不全（MR）治疗是一种有前途的选择。与变性MR不同，在变性MR中显然首选修复疗法，而对于FMR的最佳方法尚未确定。新型二尖瓣修复设备面临的挑战是证明对高风险患者的医疗管理具有安全性和出色的功效。经导管二尖瓣置换术正在作为一种可行的治疗方法出现，但需要大量的额外临床试验来确定其在治疗与MR相关的心力衰竭中的地位。

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《Heart failure clinics》 |2015年第2期|共18页
作者
Sarraf Mohammad; Feldman Ted;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Mitral regurgitation; Mitral valve; Valve replacement; Heart failure;

机译：二尖瓣关闭不全;二尖瓣;瓣膜置换;心力衰竭;

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1. Treatment of functional mitral valve regurgitation with the permanent percutaneous transvenous mitral annuloplasty system: Results of the multicenter international Percutaneous Transvenous Mitral Annuloplasty System to Reduce Mitral Valve Regurgitation in Patients with Heart Failure trial [J] . MacHaalanyJ., BilodeauL., HoffmannR., The American heart journal . 2013,第5期

机译：永久性经皮经皮二尖瓣瓣环成形术系统治疗功能性二尖瓣反流：国际多中心经皮经皮二尖瓣瓣膜成形术系统减少心力衰竭患者二尖瓣反流的结果
2. Staged percutaneous coronary intervention followed by minimally invasive mitral valve surgery versus combined coronary artery bypass graft and mitral valve surgery for two-vessel coronary artery disease and moderate to severe ischemic mitral regurgitation [J] . Christos G. Mihos, Steve Xydas, Roy F. Williams, Journal of Thoracic Disease . 2017,第7期

机译：分期经皮冠状动脉介入治疗，然后微创二尖瓣手术与联合冠状动脉搭桥术和二尖瓣手术相结合，可治疗两支冠状动脉疾病和中度至重度缺血性二尖瓣反流
3. Staged percutaneous coronary intervention followed by minimally invasive mitral valve surgery versus combined coronary artery bypass graft and mitral valve surgery for two-vessel coronary artery disease and moderate to severe ischemic mitral regurgitation [J] . Christos G. Mihos, Steve Xydas, Roy F. Williams, Journal of Thoracic Disease . 2017,第7期

机译：分期经皮冠状动脉介入治疗，然后微创二尖瓣手术与联合冠状动脉搭桥术和二尖瓣手术相结合，可治疗两支冠状动脉疾病和中度至重度缺血性二尖瓣反流
4. The value of interventional mitral valve repair in patients with ischemic or functional mitral valve regurgitation [C] . Reichenspurner Hermann, Conradi Lenard, Baldus Stephan International Congress on Coronary Artery Disease . 2011

机译：缺血性或功能二尖瓣反流患者介入二尖瓣修复的价值
5. Development of an ex vivo Pulsatile Heart Model of Functional Mitral Regurgitation to Facilitate Posterior Papillary Muscle Geometric Studies and Subvalvular Surgical Strategy [D] . Kradangnga, Krishaporn. 2018

机译：促进功能二尖瓣脉络模型的开发促进乳头状肌肉几何研究和亚瓣膜外科策略
6. Staged percutaneous coronary intervention followed by minimally invasive mitral valve surgery versus combined coronary artery bypass graft and mitral valve surgery for two-vessel coronary artery disease and moderate to severe ischemic mitral regurgitation [O] . Christos G. Mihos, Steve Xydas, Roy F. Williams, 2017

机译：分期经皮冠状动脉介入治疗然后微创二尖瓣手术与联合冠状动脉搭桥术和二尖瓣手术相结合可治疗两支冠状动脉疾病和中度至重度缺血性二尖瓣反流
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Percutaneous Intervention for Mitral Regurgitation

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