Practice guidelines on NAFLD

ChalasaniN.; PalmerM.

首页> 外文期刊>Hepatology: Official Journal of the American Association for the Study of Liver Diseases >Practice guidelines on NAFLD

【24h】

Practice guidelines on NAFLD

机译：NAFLD实践准则

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

I read with interest the practice guidelines on nonalcoholic fatty liver disease (NAFLD), in which the authors fail to reference the association between high fructose corn syrup (HFCS) and NAFLD. The intake of HFCS, a combination of glucose and fructose, has increased over time and parallels both the obesity and NAFLD epidemics. Numerous studies demonstrate that the mechanism by which HFCS causes NAFLD is due to fructose. In animal models, fructose causes steatosis and fibrosis3' by either increasing hepatic lipogenesis, causing activation of pyruvate dehydrogenase, activating inflammatory pathways,6 or up-regulating the expression of sterol regulatory element-binding protein (SREBP).7In humans, excessive fructose intake can lead to increased hepatic lipid deposition, greater insulin resistance, and hypertriglyceridemia.8 NAFLD patients have been found to drink more HFCS soft drinks compared with healthy controls. A retrospective analysis of 341 NAFLD adults found that those consuming high fructose diets had more fibrosis than those consuming low fructose diets. A prospective controlled trial witri histologic endpoints is needed to define the amount of HFCS safe for NAFLD patients and to determine the extent to which fructose contributes to the pathogenesis and progression of NAFLD. However, there are currently sufficient data to recommend that NAFLD patients refrain from excessive consumption of HFCS.

机译：我感兴趣地阅读了非酒精性脂肪肝疾病（NAFLD）的实践指南，其中作者没有提及高果糖玉米糖浆（HFCS）与NAFLD之间的关联。 HFCS（葡萄糖和果糖的组合）的摄入量随时间增加，与肥胖症和NAFLD流行同时发生。大量研究表明，HFCS引起NAFLD的机制是由于果糖引起的。在动物模型中，果糖通过增加肝脏脂肪生成，引起丙酮酸脱氢酶激活，激活炎症途径6或上调固醇调节元件结合蛋白（SREBP）的表达而引起脂肪变性和纤维化3'。7在人类中，果糖摄入过多可以导致肝脏脂质沉积增加，胰岛素抵抗增强和高甘油三酯血症。8与健康对照组相比，NAFLD患者被发现喝更多的HFCS软饮料。对341名NAFLD成人的回顾性分析发现，与低果糖饮食相比，高果糖饮食的纤维化程度更高。需要一项前瞻性对照Witri组织学终点研究来确定对NAFLD患者安全的HFCS量，并确定果糖在NAFLD发病机理和进展中的作用程度。但是，目前有足够的数据建议NAFLD患者避免过量食用HFCS。

著录项

来源
《Hepatology: Official Journal of the American Association for the Study of Liver Diseases》 |2013年第2期|共1页
作者
ChalasaniN.; PalmerM.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词

相似文献

外文文献
中文文献
专利

1. Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society [J] . Petroff David, Blueher Matthias, Wiegand Johannes Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver . 2018,第7期

机译：关于德国人和easl-easo-Easo Nafld-指南的知识与实践 - 德国肥胖学会成员
2. Practice patterns in NAFLD and NASH: real life differs from published guidelines [J] . Mary E. Rinella, Zurabi Lominadze, Rohit Loomba, Therapeutic advances in gastroenterology. . 2016,第1期

机译：NAFLD和NASH中的实践模式：现实生活与已发布的指南有所不同
3. From NAFLD in clinical practice to answers from guidelines [J] . NascimbeniF., PaisR., BellentaniS., Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2013,第4期

机译：从临床实践中的NAFLD到指南的答案
4. Clinical Practice Guideline Management Information Systems: Cancer Guidelines as Boundary Spanning Tranformable Objects of Practice [C] . Akoumianakis Demosthenes, Milolidakis Giannis, Akrivos Anargyros, 2010 2nd International Conference on Intelligent Networking and Collaborative Systems . 2010

机译：临床实践指南管理信息系统：癌症指南作为跨越实践的可变形对象的边界
5. A comparison of blood transfusion practice guidelines: What quality of evidence is being utilized to develop transfusion guideline recommendations? [D] . Man, Janice Y. 2011

机译：输血实践指南的比较：正在使用什么证据质量来制定输血指南建议？
6. Practice patterns in NAFLD and NASH: real life differs from published guidelines [O] . Mary E. Rinella, Zurabi Lominadze, Rohit Loomba, 2016

机译：NAFLD和NASH中的实践模式：现实生活与已发布的指南有所不同
7. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation31This document was approved by the American College of Cardiology Board of Trustees in August 2001, the American Heart Association Science Advisory and Coordinating Committee in August 2001, and the European Society of Cardiology Board and Committee for Practice Guidelines and Policy Conferences in August 2001.32When citing this document, the American College of Cardiology, the American Heart Association, and the European Society of Cardiology would appreciate the following citation format: Fuster V, Rydén LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, Halperin JL, Kay GN, Klein WW, Lévy S, McNamara RL, Prystowsky EN, Wann LS, Wyse DG. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation). J Am Coll Cardiol 2001;38:XX-XX.33This document is available on the World Wide Web sites of the American College of Cardiology (www.acc.org), the American Heart Association (www.americanheart.org), the European Society of Cardiology (www.escardio.org), and the North American Society of Pacing and Electrophysiology (www.naspe.org). Single reprints of this document (the complete Guidelines) to be published in the mid-October issue of the European Heart Journal are available by calling +44.207.424.4200 or +44.207.424.4389, faxing +44.207.424.4433, or writing Harcourt Publishers Ltd, European Heart Journal, ESC Guidelines – Reprints, 32 Jamestown Road, London, NW1 7BY, United Kingdom. Single reprints of the shorter version (Executive Summary and Summary of Recommendations) published in the October issue of the Journal of the American College of Cardiology and the October issue of Circulation, are available for $5.00 each by calling 800-253-4636 (US only) or by writing the Resource Center, American College of Cardiology, 9111 Old Georgetown Road, Bethesda, Maryland 20814. To purchase bulk reprints specify version and reprint number (Executive Summary 71-0208; full text 71-0209) up to 999 copies, call 800-611-6083 (US only) or fax 413-665-2671; 1000 or more copies, call 214-706-1466, fax 214-691-6342; or E-mail: pubauth@heart.org. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the North American Society of Pacing and Electrophysiology [O] . Fuster Valentin, Rydén Lars E., Asinger Richard W., 2001

机译：ACC / AHA / ESC治疗房颤患者指南31该文件于2001年8月获得美国心脏病学会董事会，2001年8月美国心脏协会科学咨询与协调委员会以及欧洲心脏病学会的批准以及实践指南和政策委员会会议（2001年8月）。32引用本文件时，美国心脏病学会，美国心脏协会和欧洲心脏病学会将赞赏以下引用格式：Fuster V，RydénLE，Asinger RW，Cannom DS，Crijns HJ，Frye RL，Halperin JL，Kay GN，Klein WW，LévyS，McNamara RL，Prystowsky EN，Wann LS，Wyse DG。 ACC / AHA / ESC治疗房颤患者的指南：美国心脏病学会/美国心脏协会实践指南工作组和欧洲心脏病学会实践指南委员会和政策会议的报告（制定指南委员会）用于房颤患者的治疗）。 J Am Coll Cardiol 2001; 38：XX-XX.33本文件可在美国心脏病学会（www.acc.org），美国心脏协会（www.americanheart.org），欧洲的万维网站点上找到心脏病学会（www.escardio.org）和北美起搏和电生理学会（www.naspe.org）。可致电+44.207.424.4200或+44.207.424.4389，传真+44.207.424.4433或写信给Harcourt Publishers，以获取本文档（完整的准则）的单份重印本（完整的准则），该印刷本将于10月中旬出版。欧洲心脏杂志，ESC指南–转载，英国伦敦詹姆斯敦路32号，NW1 7BY。短版（执行摘要和建议摘要）的单版重印在《美国心脏病学会杂志》十月刊和《循环》十月刊上，致电800-253-4636（仅美国），每本售价5.00美元。）或写信给美国心脏病学院资源中心，地址是：马里兰州贝塞斯达市Old Georgetown Road 9111，邮编20814。要购买批量转载，请指定版本和转载编号（执行摘要71-0208；全文71-0209），最多999份，致电800-611-6083（仅限美国）或传真413-665-2671； 1000或更多副本，请致电214-706-1466，传真214-691-6342;或电子邮件：pubauth@heart.org。美国心脏病学会/美国心脏协会实践指南工作组和欧洲心脏病学会实践指南和政策会议（制定房颤患者治疗指南委员会）的报告是与北方合作开发的美国起搏与电生理学会
8. Innovative Development of Evidence-Based, Medical Evacuation Clinical Practice Guidelines and Novel Validation of the Current Critical Care Air Transport Team Clinical Practice Guideline. [R] . Petro, M., Rodriquez, D., Fowler, J., 2018

机译：基于证据的医疗后送临床实践指南的创新发展和当前重症监护航空运输团队临床实践指南的新颖验证。

Practice guidelines on NAFLD

摘要

著录项

相似文献

相关主题

期刊订阅