Melanoma and immunotherapy.

Eggermont AM; Schadendorf D

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Melanoma and immunotherapy.

机译：黑色素瘤和免疫疗法。

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About 20% of all primary melanomas will spread. The likelihood of metastatic behavior correlates with prognostic factors such as tumor thickness, mitotic index, presence of ulceration, lymphocyte infiltration, age, gender, and anatomic site. Immunotherapies are developed for melanoma patients in stage IV who have distant metastases and in stage II to III patients in the adjuvant micrometastatic setting, where only a fraction of patients have widespread (microscopic) disease.

机译：所有原发性黑色素瘤中约有20％会扩散。转移行为的可能性与预后因素相关，例如肿瘤厚度，有丝分裂指数，溃疡的存在，淋巴细胞浸润，年龄，性别和解剖部位。针对具有远处转移的IV期黑色素瘤患者和处于辅助微转移环境的II至III期患者开发了免疫疗法，其中只有一小部分患者患有广泛的（微观）疾病。

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来源
《Hematology/Oncology Clinics of North America》 |2009年第3期|共10页
作者
Eggermont AM; Schadendorf D;
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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Melanoma; Immunotherapy; Diagnostic Neoplasm Staging; Roman Numeral IV; behavioral aspects; *黑色素瘤; 免疫疗法;

机译：Melanoma;Immunotherapy;Diagnostic Neoplasm Staging;Roman Numeral IV;behavioral aspects;*黑色素瘤;免疫疗法;

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专利

1. Concordant loss of melanoma differentiation antigens in synchronous and asynchronous melanoma metastases: implications for immunotherapy. [J] . Trefzer U, Hofmann M, Reinke S, Melanoma research . 2006,第2期

机译：黑色素瘤分化抗原在同步和异步黑色素瘤转移中的一致丧失：对免疫疗法的影响。
2. Melanoma-inhibitory activity protein concentrations in blood of melanoma patients treated with immunotherapy. [J] . Dreau D, Bosserhoff AK, White RL, Oncology Research . 1999,第1期

机译：用免疫疗法治疗的黑素瘤患者血液中的黑素瘤抑制活性蛋白浓度。
3. T-cell immune function in tumor, skin, and peripheral blood of advanced stage melanoma patients: implications for immunotherapy. [J] . Tjin EP, Konijnenberg D, Krebbers G, Clinical cancer research: an official journal of the American Association for Cancer Research . 2011,第17期

机译：晚期黑色素瘤患者的肿瘤，皮肤和外周血中的T细胞免疫功能：对免疫治疗的意义。
4. BIBS, a New Descriptor for Melanoma/Non-Melanoma Discrimination [C] . Saeid Amouzad Mahdiraji, Yasser Baleghi, Sayed Mahmoud Sakhaei Iranian Conference on Electrical Engineering . 2018

机译：BIBS，黑色素瘤/非黑色素瘤歧视的新描述
5. Multi-Compartmental Delivery Systems for Peptide and DNA Vaccines in Melanoma Immunotherapy. [D] . Kalariya, Mayurkumar. 2012

机译：黑色素瘤免疫疗法中肽和DNA疫苗的多隔室递送系统。
6. Melanoma immune surveillance and immunotherapy. [O] . S Ferrone 1994

机译：黑色素瘤免疫监视和免疫疗法。
7. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. [O] . Holtzhausen, A, Zhao, F, Evans, KS, 2015

机译：黑色素瘤衍生的Wnt5a促进IDO和免疫耐受的局部树突细胞表达：药理学增强免疫疗法的机会。

Melanoma and immunotherapy.

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