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Adult immunization with 13-valent pneumococcal vaccine in Campania region, South Italy: An economic evaluation

机译：意大利南部坎帕尼亚地区的成人用13价肺炎球菌疫苗进行成人免疫接种：一项经济评估

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Pneumococcal pneumonia has a high clinical burden in terms of morbidity, mortality and hospitalization rate, with heavy implications for worldwide health systems. In particular, higher incidence and mortality rates of community-acquired pneumonia (CAP) cases, with related costs, are registered among elderly. This study aimed to an economic evaluation about the immunization with PCV13 in the adult population in Campania region, South Italy. For this purpose we performed, considering a period of 5 y, a budget impact analysis (BIA) and a cost-effectiveness analysis which considered 2 scenarios of immunization compared with lack of immunization for 2 targeted cohorts: first, the high risk subjects aged 50-79 y, and second the high risk individuals aged 50-64 y, together with all those aged 65 y. Regarding the first group, the decrease of pneumonia could give savings equal to ?29 005 660, while the immunization of the second cohort could allow savings equal to ?10006017.The economic evaluation of pneumococcal vaccine for adult groups represents an essential instrument to support health policies. This study showed that both hypothesized immunization strategies could produce savings. Obtained results support the use of pneumococcal conjugate vaccine for adults. This strategy could represent a sustainable and savings-producer health policy.
机译：肺炎球菌性肺炎在发病率，死亡率和住院率方面具有很高的临床负担，对全球卫生系统具有重大影响。尤其是，老年人中社区获得性肺炎（CAP）病例的发生率和死亡率较高，且相关费用较高。这项研究旨在对意大利南部坎帕尼亚地区的成年人群中PCV13的免疫接种进行经济评估。为此，我们考虑了5年的时间，进行了预算影响分析（BIA）和成本效益分析，其中考虑了2种目标人群的2种免疫方案与未进行免疫的情况：首先，年龄50岁的高风险受试者-79岁，其次是50-64岁的高风险人群，以及所有65岁的人群。对于第一类人群，肺炎的减少可节省约29 005 660欧元，而第二类人群的免疫则可节省约10006017英镑。成人肺炎球菌疫苗的经济评估是支持健康的重要手段政策。这项研究表明，两种假定的免疫策略均可以节省费用。获得的结果支持成人使用肺炎球菌结合疫苗。该战略可以代表一项可持续的储蓄生产者健康政策。

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