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首页> 外文期刊>Drugs of today: Medicamentos de actualidad >The management of fibromyalgia.
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The management of fibromyalgia.

机译：纤维肌痛的管理。

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摘要

Fibromyalgia is one of a number of overlapping "functional somatic syndromes", including irritable bowel syndrome, tension headache, chronic idiopathic lower back pain, chronic fatigue syndrome and others. These conditions affect females more frequently than males and probably share common underlying neurobiological mechanisms, as well as frequent psychological, cognitive and behavioral comorbidities. Since the pain in these conditions is most likely "central" in origin, classes of drugs such as nonsteroidal antiinflammatory drugs (NSAIDs) and opioids, which are quite effective for "peripheral" pain, are relatively ineffective for the pain seen in these syndromes. Instead, tricyclic and other classes of antidepressants, antiseizure drugs and a number of other neuroactive compounds seem to be more effective. In addition, nonpharmacological therapies such as aerobic exercise and cognitive behavioral therapy are quite effective and frequently underutilized in clinical practice. (c) 2004 Prous Science. Allrights reserved.
机译：纤维肌痛是许多重叠的“功能性躯体综合症”之一，包括肠易激综合症，紧张性头痛，慢性特发性下背部疼痛，慢性疲劳综合症等。与男性相比，这些疾病对女性的影响更大，并且可能具有共同的潜在神经生物学机制以及频繁的心理，认知和行为合并症。由于这些情况下的疼痛很可能是起源于“中央”的，因此对于“周围”疼痛非常有效的非甾体抗炎药（NSAIDs）和阿片类药物之类的药物对这些综合征所见的疼痛相对无效。相反，三环和其他类别的抗抑郁药，抗癫痫药和许多其他神经活性化合物似乎更有效。此外，有氧运动和认知行为疗法等非药物疗法非常有效，在临床实践中经常使用不足。 （c）2004 Prous科学。版权所有。

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