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首页> 外文期刊>Circulation journal >Metabolic Syndrome and Risk of Recurrence of Atrial Fibrillation After Catheter Ablation
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Metabolic Syndrome and Risk of Recurrence of Atrial Fibrillation After Catheter Ablation

机译：导管消融后代谢综合征和房颤复发的风险

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Background: Metabolic syndrome (MetS), as well as several risk factors of cardiovascular diseases, is known to be associated with atrial fibrillation (AF), but its impact on the recurrence of AF after catheter ablation has not been explored.Methods and Results: The data for 654 consecutive AF patients who underwent an index circumferential pulmonary vein ablation were retrospectively analyzed. Of them, 323 (49.4%) had MetS according to the modified National Cholesterol Education Program-Adult Treatment Panel HI criteria and Chinese ethnic criteria. After a mean follow-up of 470+-323 (91-1,245) days, patients with MetS had a significantly higher incidence of AF recurrence (43.7%) compared with non-MetS patients (30.5%, P<0.001). Univariate analysis revealed that non-paroxysmal AF, left atrial size, MetS and body mass index were predictors of AF recurrence. Multivariate analysis revealed that MetS (hazard ratio=1.64, 95%confidence interval (CI) 1.07-2.49, P=0.022) and nonparoxysraal AF (hazard ratio =1.57, 95%CI 1.15-2.14, P=0.004) were independent predictors of AF recurrence. The major complications rate did not differ between the MetS and the non-MetS groups (1.86% vs 2.42%, P=0.621). Conclusions: MetS diagnosed prior to AF ablation is an independent predictor of AF recurrence.
机译：背景：代谢综合征（MetS）以及几种心血管疾病的危险因素与房颤（AF）有关，但尚未探讨其对导管消融后房颤复发的影响。方法和结果：回顾性分析了654例连续性AF患者行指数圆周肺静脉消融术的数据。根据修订的《国家胆固醇教育计划-成人治疗小组HI》标准和中国民族标准，其中323人（占49.4％）患有MetS。在平均随访470 + -323（91-1,245）天后，与非MetS患者相比，MetS患者的AF复发率（43.7％）显着高于非MetS患者（30.5％，P <0.001）。单因素分析显示，非阵发性房颤，左心房大小，MetS和体重指数是房颤复发的预测因素。多变量分析显示，MetS（危险比= 1.64，95％置信区间（CI）1.07-2.49，P = 0.022）和非阵发性AF（危险比= 1.57，95％CI 1.15-2.14，P = 0.004）是以下因素的独立预测因子AF复发。 MetS组和非MetS组之间的主要并发症发生率没有差异（1.86％对2.42％，P = 0.621）。结论：房颤消融前诊断的MetS是房颤复发的独立预测因子。

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