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首页> 外文期刊>Circulation journal >Conduction abnormality and arrhythmia after transcatheter closure of atrial septal defect
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Conduction abnormality and arrhythmia after transcatheter closure of atrial septal defect

机译：经导管封闭房间隔缺损后的传导异常和心律不齐

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Background: The aim of this study was to prospectively perform ambulatory 24-h ECG monitoring to assess the effects of transcatheter closure of atrial septal defect (ASD).Methods and Results: A total of 235 consecutive subjects (female, n=163; male, n=72; age, 44.6±14.4 years) were enrolled in the study, who were due undergo ASD closure. Holter monitoring was performed before procedure and at 1, 6 and 12 months of follow-up. During the procedure transient supraventricular arrhythmia occurred in 8 patients (3.4%), and bradycardia in 3 (1.3%). In 3 patients (1.3%) an episode of atrial fibrillation occurred in the first hour after the procedure. In 8 patients (3.4%) transient first-degree atrioventricular block was noted. A significant increase in number of supraventricular extrasystoles (SVES)/24 h was noted 1 month after the procedure (P<0.001). On multiple forward stepwise regression analysis, device size and fluoroscopy time had an influence on increase in number of SVES seen 1 month after the procedure (P<0.001).Conclusions: Transcatheter closure of ASD is associated with a transient increase in supraventricular premature beats and a small risk of conduction abnormalities and paroxysmal atrial fibrillation in early follow-up. Transcatheter closure of ASD does not reduce arrhythmia that appears prior to ASD closure. Larger device size and longer procedure time are associated with increased risk of supraventricular arrhythmia on early follow-up.
机译：背景：本研究的目的是前瞻性进行24小时动态心电图监测，以评估经导管封闭房间隔缺损（ASD）的效果。方法和结果：共有235名连续受试者（女，n = 163;男） ，n = 72;年龄为44.6±14.4岁）参加了这项研究，他们将接受ASD封闭治疗。动态心电图监测在手术前以及术后1、6和12个月进行。在该过程中，发生短暂性室上性心律失常8例（3.4％），心动过缓3例（1.3％）。在3例患者（1.3％）中，在手术后的第一小时发生了房颤发作。在8例患者中（3.4％）出现短暂性一级房室传导阻滞。手术后1个月，室上收缩期（SVES）/ 24 h明显增加（P <0.001）。在多步逐步回归分析中，装置尺寸和透视时间对手术后1个月内观察到的SVES数量增加有影响（P <0.001）。结论：ASD的经导管闭合与室上早搏的短暂增加有关。在早期随访中出现传导异常和阵发性房颤的风险很小。经导管关闭ASD并不能减少ASD关闭前出现的心律不齐。较大的器械尺寸和较长的手术时间与早期随访时室上性心律失常的风险增加有关。

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