• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Japanese circulation journal >Exercise beta-methyl iodophenyl acid (BMIPP) and resting thalium delayed single photon emission computed tomography (SPECT) in the assessment of ischemia and viability.
【24h】

Exercise beta-methyl iodophenyl acid (BMIPP) and resting thalium delayed single photon emission computed tomography (SPECT) in the assessment of ischemia and viability.

机译：运动性β-甲基碘代苯甲酸（BMIPP）和静息延迟单光子发射计算机断层扫描（SPECT）可评估缺血和生存能力。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To clarify the significance of exercise BMIPP (beta-methyl iodophenyl pentadecanoic acid) and resting T1 delayed single photon emission computed tomography (SPECT) in the assessment of ischemia and viability, we studied maximal exercise-loading BMIPP SPECT following rest-injected T1 3 h SPECT in 11 control subjects, 20 patients with effort angina and 38 patients with old myocardial infarction. The left ventricular wall on ECT was divided into 9 segments. BMIPP and T1 uptake were scored as 0 = normal, 1 = reduced, 2 = severely reduced, or 3 = absent. Discordance was defined as when segments with a reduced BMIPP uptake had a better resting T1 uptake. Significant coronary artery stenosis was defined as stenosis of 75% or greater on coronary arteriogram. Left ventricular wall motion was assessed as either normokinesis, hypokinesis, severe hypokinesis, akinesis or dyskinesis on left ventriculogram. When discordance was considered to be a marker of ischemia, the sensitivity and specificity in effort angina and control subjects were 95.2% and 84.6% for patients and 83.9% and 94.4% for diseased vessels, respectively. There were no differences between the sensitivity and specificity in left anterior descending artery (LAD), left circumflex artery (LCx) and right coronary artery (RCA) lesions (83.3%, 95.5% in LAD, 83.3%, 95.5% in LCx, 85.7%, 92.6% in RCA, respectively). All of the patients with old myocardial infarction had reduced exercise BMIPP uptake in infarcted regions. In old myocardial infarction, 35 patients had segments with discordant uptake. Discordance was observed in 75 (91.5%) of 82 segments with hypokinesis, and in 24 (92.3%) of 26 segments with severe hypokinesis. Even among the 36 segments with akinesis or dyskinesis, 25 (69.0%) had discordant uptake. When discordance in the infarcted region was considered to be a marker of viability, regions with severe asynergy showed a high possibility of viability. Thus, discordant uptake on exercise BMIPP and resting T1 delayed SPECT may be a useful marker of ischemia in effort angina and of viability in old myocardial infarction.
机译：为了阐明运动BMIPP（β-甲基碘苯基十五烷酸）和静息T1延迟单光子发射计算机断层扫描（SPECT）在评估缺血性和生存能力中的重要性，我们研究了静注T1 3 h后最大运动负荷BMIPP SPECT在11名对照受试者，20名努力型心绞痛患者和38名老年心肌梗死患者中进行SPECT。 ECT的左心室壁分为9个部分。 BMIPP和T1摄取分为0 =正常，1 =降低，2 =严重降低或3 =不存在。不一致性定义为BMIPP摄取减少的区段何时具有更好的静息T1摄取。冠状动脉狭窄的严重程度定义为冠状动脉造影上的狭窄率为75％或更高。左心室图评估左室壁运动为正常运动，运动不足，严重运动不足，运动或运动障碍。当不一致被认为是局部缺血的标志物时，努力型心绞痛和对照组受试者的敏感性和特异性分别为患者的95.2％和84.6％，以及患病血管的83.9％和94.4％。左前降支（LAD），左旋支动脉（LCx）和右冠状动脉（RCA）病变的敏感性和特异性无差异（LAD为83.3％，95.5％，LCx为83.3％，95.5％，85.7）百分比，RCA分别为92.6％）。所有患有老年心肌梗塞的患者在梗塞区域的运动BMIPP摄取均降低。在旧的心肌梗塞中，有35名患者的节段摄取不协调。在运动功能减退的82个节段中，有75个（91.5％）出现不一致;在运动功能严重减退的26个节段中，有24个（92.3％）存在不一致。甚至在有运动或运动障碍的36个部分中，有25个（69.0％）的摄取不协调。当将梗死区域的不一致性视为生存能力的标志时，具有严重无协同作用的区域显示出生存能力的可能性很高。因此，运动BMIPP和静息T1延迟SPECT的不均衡摄取可能是努力型心绞痛缺血和老年心肌梗死生存力的有用标志。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号