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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Comparison of cobalt chromium, ceramic and pyrocarbon hemiprosthesis in a rabbit model: Ceramic leads to more cartilage damage than cobalt chromium.
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Comparison of cobalt chromium, ceramic and pyrocarbon hemiprosthesis in a rabbit model: Ceramic leads to more cartilage damage than cobalt chromium.

机译：在兔子模型中比较钴铬，陶瓷和热碳半假体：与钴铬相比，陶瓷导致的软骨损伤更大。

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摘要

Cartilage wear after hemiarthroplasty remains a problem in orthopedic surgery. The main cause of cartilage wear, apart from incongruency of the joint partners, is generally considered to be the tribology of the material surfaces. This study evaluates in 27 rabbits the degree of cartilage wear of the tibia plateau after hemiarthroplasty with proximal interphalangeal prostheses made of three different materials [cobalt chromium (CoCr), pyrocarbon (PyCa), and ceramic (Cer)]. Three months after hemiarthroplasty, the articulating tibial cartilage was histomorphologically examined and degenerative damage was graded using the modified Mankin score. The mechanical capacity of the cartilage was assessed by stress relaxation testing. The biomechanical properties of the cartilage were significantly superior in the CoCr group as compared with the Cer group (p < 0.03), indicating less damage to the articulating cartilage surface. The Mankin score showed significantly lower values in the CoCr compared with Cer group (p = 0.011), whereas no differences were found between PyCa and CoCr or PyCa and Cer. In contrast to earlier reports, in this hemiarthroplasty model, the CoCr alloy showed less cartilage damage than a ceramic surface. Further, in vivo experiments are necessary to elucidate the controversial issue of the most suitable material for hemiarthroplasty.
机译：假体置换术后的软骨磨损仍然是整形外科的问题。除了关节伙伴的不协调之外，软骨磨损的主要原因通常被认为是材料表面的摩擦学。这项研究评估了27只兔子在髋关节置换术后胫骨平台的软骨磨损程度，该假体采用由三种不同材料[钴铬（CoCr），热碳（PyCa）和陶瓷（Cer）]制成的近端指间假体。半髋关节置换术后三个月，对组织的胫骨软骨进行组织形态学检查，并使用改良的Mankin评分对退行性损伤进行分级。通过应力松弛测试评估软骨的机械容量。与Cer组相比，CoCr组的软骨生物力学性能明显优越（p <0.03），表明对关节软骨表面的损伤较小。与Cer组相比，ManCr评分显示CoCr值显着较低（p = 0.011），而PyCa和CoCr或PyCa和Cer之间没有差异。与早期报道相反，在这种半髋关节置换模型中，CoCr合金的软骨损伤比陶瓷表面小。此外，必须进行体内实验来阐明有争议的最适合半髋关节置换材料的问题。

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