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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Thyroid nodules: re-evaluation with ultrasound.
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Thyroid nodules: re-evaluation with ultrasound.

机译：甲状腺结节：超声重新评估。

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摘要

The purpose of this study was to clarify ultrasound (US) evaluation of microcalcifications and determine whether the calcifications seen in US scans can reliably predict malignant thyroid tumors. Diagnostic accuracy of microcalcification and other various signs seen in US scans for predicting malignancy was evaluated prospectively in 259 pathologically verified thyroid nodules. Sonographic and pathologic correlation of calcifications was performed on 69 of 99 surgically removed nodules. Pathologic studies revealed that hyperechoic areas with acoustic shadowing represented mostly amorphous dense calcifications and sometimes microcalcifications, but small particles without acoustic shadowing mainly reflected microcalcifications and sometimes large amount of fibrous bands and condensed colloids. Of the various sonographic signs, microcalcification showed the highest accuracy (76%), specificity (93%), and positive predictive value (70%) for malignancy as a single sonographic sign, but its sensitivity (36%)was poor. Although sonographic microcalcification showed relatively high specificity, the accuracy of this finding for malignancy was insufficient.
机译：这项研究的目的是阐明超声（US）对微钙化的评估，并确定在US扫描中看到的钙化是否可以可靠地预测甲状腺恶性肿瘤。前瞻性评估了259个经病理证实的甲状腺结节，评估了在美国扫描中发现的微钙化和其他各种征兆对恶性肿瘤的诊断准确性。对99个手术切除的结节中的69个进行了钙化的超声和病理学相关性分析。病理学研究表明，带有回声阴影的高回声区大部分代表无定形的致密钙化，有时代表微钙化，而没有回声阴影的小颗粒则主要反映出微钙化，有时反映了大量的纤维带和凝聚的胶体。在各种超声检查征象中，微钙化显示作为单一超声检查征象的恶性度最高（76％），特异性（93％）和阳性预测值（70％），但其敏感性（36％）很差。尽管超声微钙化显示相对较高的特异性，但该发现对恶性肿瘤的准确性仍不足。

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