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首页> 外文期刊>Journal of cosmetic dermatology >Cumulative irritation patch test of sanitary pads on sensitive skin
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Cumulative irritation patch test of sanitary pads on sensitive skin

机译：敏感皮肤上卫生护垫的累积刺激斑贴试验

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Background Tools are needed to assess the effects of various products on sensitive skin. Aim To investigate the cutaneous compatibility of various sanitary pads in people with self-declared sensitive skin.Patients /methods Eight subjects, who considered their skin to be sensitive and who reported adverse skin responses to everyday products or clothing, were patch tested on the arm with two, low-irritancy sanitary pads for four consecutive 24-hour periods. Test products differed only in their surface covering. Sodium lauryl sulfate solution (0.1% w/v) and physiological saline served as standard irritant and nonirritant controls, respectively. Skin irritation (erythema) was graded after each 24-hour period.Results No significant difference in skin erythema scores was observed between groups (scores on day 4:1.06 (+-) 0.11 vs. 1.25 (+-) 0.13, on a five-point scale, P < 0.05). The temporal development of cumulative irritation associated with the pads was comparable to that observed with the nonirritant control (a plateau in maximal group scores) and distinct from that of the irritant control (continuously rising scores).Conclusion Sanitary pads under investigation elicited negligible cumulative irritation in a four-day patch test on subjects with self-declared sensitive skin. The temporal pattern of cumulative response was consistent with the inherently low irritation potential of the products.
机译：需要背景工具来评估各种产品对敏感皮肤的影响。目的研究自称敏感皮肤的人各种卫生护垫的皮肤相容性。患者/方法对八名认为自己的皮肤敏感并报告了对日常产品或衣服的皮肤反应不良的受试者进行手臂贴剂测试连续四个24小时使用两个低刺激性卫生巾。测试产品仅在表面覆盖方面有所不同。月桂基硫酸钠溶液（0.1％w / v）和生理盐水分别用作标准刺激物和非刺激物对照。每隔24小时对皮肤刺激（红斑）进行分级。结果两组之间的皮肤红斑得分没有显着差异（第5天的评分分别为：1.06（+-）0.11和1.25（+-）0.13）点量表，P <0.05）。与垫相关的累积刺激的时间发展与非刺激性对照所观察到的时间发展相当（最大组得分处于平稳状态），并且与刺激性对照的观察发展（持续上升的评分）不同。在四天的自测敏感皮肤受试者的斑贴测试中。累积反应的时间模式与产品固有的低刺激性相一致。

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