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Marine Sponges as a Drug Treasure

机译：海洋海绵作为毒品宝藏

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Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge's derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines.
机译：就其次生代谢物的巨大潜力而​​言，海洋海绵已被视为毒品宝库。大多数研究是针对海绵衍生的化合物进行的，以检查其药理特性。这类化合物被证明具有抗菌，抗病毒，抗真菌，抗疟疾，抗肿瘤，免疫抑制和心血管活性。尽管到目前为止，尚不清楚许多化合物干扰人类发病机理的作用方式，但在本综述中，不仅在体外和体内检查了药物对严重病原微生物的能力，而且该方式用图解说明了药用化合物的作用。该知识是尤其是在将药物分子转化为药物时已知的基本成分之一。海绵会产生另一种具有大量碳骨架的化学物质，这些化学物质已被发现是在不同部位干扰人类发病机制的主要成分。不同疾病具有在体内不同部位进行战斗的能力这一事实可以增加生产针对性药物的机会。

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