• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of glaucoma >Polarimetric measurement of retinal nerve fiber layer thickness in glaucoma diagnosis.
【24h】

Polarimetric measurement of retinal nerve fiber layer thickness in glaucoma diagnosis.

机译：极化测量视网膜神经纤维层厚度在青光眼诊断中的作用。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To evaluate reliability and diagnostic value of polarimetric measurements of the retinal nerve fiber layer (RNFL) thickness in the diagnosis of glaucoma. METHODS: The study included 81 eyes with perimetric glaucoma with glaucomatous changes of the optic disc and visual field defects; 52 eyes with preperimetric glaucoma with glaucomatous optic disc abnormalities and normal achromatic visual fields; and 70 normal eyes. For determination of reliability, four examiners repeated polarimetric measurements five times in ten normal subjects. RESULTS: The polarimetric variables were significantly correlated with increasing mean visual field defect and decreasing neuroretinal rim area. In correlation analyses with visual field defects, correlation coefficients were highest for the variable "superiorasal ratio" and "the Number," a variable calculated by the neural network of the device. In correlations with neuroretinal rim area, correlation coefficients were highest for measurements of the inferior nerve fiber layer thickness. The preperimetric glaucoma group and the control group differed significantly in the variables "superiorasal ratio" and "the Number" and, to a smaller degree, in the variables "superior/temporal ratio" and "superior/inferior ratio." The Number variable had a sensitivity of 82% and 58% at a predefined specificity of 80% in separating perimetric glaucoma patients and preperimetric glaucoma patients, respectively, from control subjects. Reproducibility of the polarimetric measurements ranged between 70% and 89%. CONCLUSION: Polarimetric measurements of the RNFL thickness can detect glaucomatous optic nerve damage in patients with visual field loss, and in some patients with preperimetric glaucomatous optic nerve damage. Considering the fast performance, easy handling, and low maintenance costs, RNFL polarimetry may be helpful in glaucoma diagnosis.
机译：目的：评估偏振光测量视网膜神经纤维层（RNFL）厚度在青光眼诊断中的可靠性和诊断价值。方法：本研究包括81只眼的视野性青光眼，并伴有视盘的青光眼改变和视野缺损。 52眼围前期青光眼，伴有青光眼视盘异常和正常消色差视野;和70正常的眼睛。为了确定可靠性，四名检查员对十名正常受试者进行了五次偏振测量。结果：旋光度变量与平均视野缺损增加和神经视网膜边缘区域减少显着相关。在具有视野缺陷的相关分析中，变量“上/鼻比”和“数字”（由设备的神经网络计算得出）的相关系数最高。与神经视网膜边缘区域的相关性，测量下神经纤维层厚度的相关系数最高。围前期青光眼组和对照组在变量“上/鼻比”和“数目”上有显着差异，在较小的程度上，变量“上/颞比”和“上/下比”也有较大差异。 Number变量在将周围性青光眼患者和周围性青光眼患者与对照组分开时，在预定义的特异性为80％时具有82％和58％的灵敏度。偏振测量的重现性介于70％和89％之间。结论：RNFL厚度的极化测量可以检测到视野丧失患者以及部分围手术期青光眼视神经损伤的青光眼视神经损伤。考虑到快速性能，易于处理和低维护成本，RNFL旋光仪可能有助于青光眼的诊断。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号