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Climb into the cage

机译:爬进笼子

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摘要

contactless three-dimensional trap-ping and manipulation of cellscan be useful for various biolog-ical studies. Such manipulation is typi-cally performed using dielectrophoresis- in which a nonuniform electric field ex-erts force on the cell - or using opticaltrapping. However, commercially avail-able dielectrophoresis systems can dam-age cells after about 30 minutes, so their- in which a nonuniform electric field ex-erts force on the cell - or using opticaltrapping. However, commercially avail-able dielectrophoresis systems can dam-age cells after about 30 minutes, so their use is limited if long-term, gentle cell han-dling with high precision is required, suchas for calcium signaling or protein traf-ficking studies. Optical trapping has sim-ilar limitations.
机译:非接触式三维捕获和细胞操纵可用于各种生物学研究。通常使用介电电泳(其中非均匀电场向细胞施加力)或使用光阱进行此类操作。但是,市售的介电泳系统会在约30分钟后损坏细胞,因此,在其中不均匀的电场会向细胞施加力(或使用光阱法)。但是,市售的介电泳系统会在约30分钟后损坏细胞,因此,如果需要长期,温和,高精度的细胞处理,例如钙信号传导或蛋白质转运研究,则它们的使用受到限制。光学陷波具有类似的局限性。

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