On the spread of morphogens

Merkin JH; Sleeman BD

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On the spread of morphogens

机译：关于形态发生素的传播

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Pattern organisation of cells and tissue are specified during embryonic development by gradients of morphogens, substances that assign different fates of cells at different concentrations. Morphogen gradients form by transport from a localized site. Whether this occurs by diffusion or some other more elaborate mechanism is controversial. Here we provide an analysis of two models considered by Lander et al. [4] used in support of the diffusive transport hypothesis.

机译：细胞和组织的模式组织在胚胎发育过程中通过形态发生剂的梯度来确定，形态发生素是指以不同浓度分配不同命运的物质。形态发生梯度是通过从本地站点传输而形成的。这是通过扩散还是其他更复杂的机制发生是有争议的。在这里，我们对Lander等人考虑的两种模型进行了分析。 [4]用于支持扩散运输假说。

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《Journal of Mathematical Biology》 |2005年第1期|共17页
作者
Merkin JH; Sleeman BD;
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正文语种 eng
中图分类生物科学;
关键词
GRADIENT FORMATION; DROSOPHILA; TRANSPORT; WINGLESS; XENOPUS; EMBRYO; DPP;

机译：梯度形成;果蝇;运输;风化;希诺普斯;胚胎;DPP;

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1. New advances in morphogen gradient formation modelling. Comment on Morphogenetic action through flux-limited spreading by M. Verbeni et al. (Note) [J] . Locker M., Perron M. Physics of life reviews . 2013,第4期

机译：形态发生子梯度形成建模的新进展。 M. Verbeni等人通过通量限制扩散对形态发生作用的评论。（注意）
2. FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain [J] . David J. Price, Wai-Kit Chan, Thomas Pratt Biology Open . 2017,第12期

机译：发育中的脑中乙酰肝素硫转移酶Hs2st和Hs6st1对FGF8形态发生因子梯度的调节发育中的脑中乙酰肝素硫转移酶Hs2st和Hs6st1对FGF8形态发生剂梯度的调控
3. Robustness of the Dorsal morphogen gradient with respect to morphogen dosage [J] . Hadel Al Asafen, Prasad U. Bandodkar, Sophia Carrell-Noel, PLoS Computational Biology . 2020,第4期

机译：与形态学剂量的背体形态梯度的鲁棒性
4. Synthetic Morphogen Fields for Directed Dental Pulp Stem Cell Differentiation [C] . Saeed Ur Rahman, Malvika Nagrath, Sasikumar Ponnusamy, Society for Biomaterials annual meeting and exposition . 2019

机译：定向牙髓干细胞分化的合成形态学领域。
5. Quantification of Morphogen Gradients and Patterning Scale Invariance along Dorsal-ventral Embryonic Axis [D] . Huang, Yan. 2018

机译：沿背腹胚轴的形态梯度定量和模式尺度不变性
6. Robustness of the Dorsal morphogen gradient with respect to morphogen dosage [O] . Hadel Al Asafen, Prasad U. Bandodkar, Sophia Carrell-Noel, 2020

机译：背部形态发生梯度相对于形态发生剂量的稳健性
7. Argosomes A Potential Vehicle for the Spread of Morphogens through Epithelia [O] . Greco Valentina, Hannus Michael, Eaton Suzanne 2001

机译：Argosomes是通过上皮细胞传播病原体的潜在媒介

On the spread of morphogens

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