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Carbon nanotubes for transdermal drug delivery

机译:碳纳米管用于透皮给药

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摘要

In this study, drug carrier properties through skin and penetration enhancement effects of carbon nanotubes (CNTs) are presented. Multi-walled and double-walled carbon nanotubes were used. Penetration enhancement into the skin following passive diffusion and iontophoresis were determined. Possible solubility enhancement effects and drug adsorption properties of CNTs were investigated. CNTs were found to be a useful drug carrier system and they can provide a high loading and enhanced transdermal penetration for especially hydrophobic drugs. The electroconductive nature of CNTs allows easy application of iontophoresis and the additional advantage of CNTs appears to be using them as electrodes.
机译:在这项研究中,通过皮肤的药物载体性质和碳纳米管(CNT)的渗透增强作用得以展示。使用了多壁和双壁碳纳米管。确定了被动扩散和离子电渗疗法后皮肤的渗透增强作用。研究了可能的碳纳米管溶解度增强作用和药物吸附性能。人们发现碳纳米管是一种有用的药物载体系统,可以为特别是疏水性药物提供高载量和增强的透皮渗透性。 CNT的导电性质使离子电渗疗法易于应用,并且CNT的另一个优点似乎是将它们用作电极。

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