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首页> 外文期刊>Journal of neuroscience, psychology, and economics >Genes, Economics, and Happiness
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Genes, Economics, and Happiness

机译：基因，经济学和幸福

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We explore the influence of genetic variation on subjective well-being by employing a twin design and genetic association study. In a nationally representative twin sample, we first show that -33% of the variation in life satisfaction is explained by genetic variation. Although previous studies have shown that baseline happiness is significantly heritable, little research has considered molecular genetic associations with subjective well-being. We study the relationship between a functional polymorphism on the serotonin transporter gene (5-HJTLPR) and life satisfaction. We initially find that individuals with the longer, transcriptionally more efficient variant of this genotype report greater life satisfaction (n = 2,545; p = .012). However, our replication attempts on independent samples produce mixed results, indicating that more work needs to be done to better understand the relationship between this genotype and subjective well-being. This work has implications for how economists think about the determinants of utility, and the extent to which exogenous shocks might affect individual well-being.
机译：我们通过采用双胞胎设计和遗传关联研究探索遗传变异对主观幸福感的影响。在全国范围内具有代表性的双胞胎样本中，我们首先表明-33％的生活满意度差异可以通过遗传差异来解释。尽管以前的研究表明，基线幸福感具有显着的遗传性，但很少有研究认为分子遗传与主观幸福感相关。我们研究5-羟色胺转运蛋白基因（5-HJTLPR）的功能多态性与生活满意度之间的关系。我们最初发现，具有该基因型更长，转录效率更高的变体的个体报告出更高的生活满意度（n = 2,545; p = .012）。但是，我们在独立样本上进行的复制尝试产生了不同的结果，表明需要做更多的工作才能更好地了解这种基因型与主观幸福感之间的关系。这项工作对经济学家如何考虑效用的决定因素以及外源冲击可能影响个人福祉的程度产生了影响。

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