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首页> 外文期刊>Clinics in dermatology >The 'dysplastic' nevus.
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The 'dysplastic' nevus.

机译:“发育不良”痣。

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摘要

Dysplastic nevi have become an increasing focus clinically, with evidence that they are associated with a higher risk of developing melanoma. However, there still is contention regarding the significance of dysplastic nevi. This contribution provides an overview of the history, epidemiology, genetics, clinical and histologic features, and procedures for clinical management of dysplastic nevi. Since dysplastic nevi were described originally in 1978, a great deal of research has examined the epidemiology of these lesions and the genetic factors related to the development of dysplastic nevi. However, there is disagreement regarding the clinical management of dysplastic nevi and the histologic definition of dysplastic nevi. Current recommendations include preventative measures, such as sun protection and careful surveillance and biopsies of suspicious lesions as needed. The advent of new technologies, such as computer-vision systems, have the potential to significantly change treatment of dysplastic nevi in the future.
机译:发育异常痣在临床上已成为越来越多的焦点,有证据表明它们与患黑色素瘤的风险较高有关。但是,关于增生痣的重要性仍然存在争议。该贡献概述了增生痣的病史,流行病学,遗传学,临床和组织学特征以及临床处理程序。自1978年最初描述增生性痣以来,大量研究已经研究了这些病变的流行病学以及与发育不良性痣的发展相关的遗传因素。然而,关于增生痣的临床管理和增生痣的组织学定义存在分歧。当前的建议包括预防措施,例如防晒和根据需要仔细监视和对可疑病变进行活检。新技术的出现,例如计算机视觉系统,有可能在未来显着改变增生痣的治疗方法。

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