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Intrahepatic cholestasis of pregnancy: Recent advances

机译:妊娠肝内胆汁淤积症:最新进展

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Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the underlying pathophysiology and mechanisms involved in adverse outcomes has previously restricted treatment options and pregnancy management. Recent advances in these research fields provide tantalizing targets to improve the care of pregnant women affected by this condition. (C) 2016 Elsevier Inc. All rights reserved.
机译:妊娠肝内胆汁淤积症(也称为产科胆汁淤积症)是妊娠瘙痒病,其特征是循环胆汁酸的潜在升高和肝脏紊乱,并与不良的胎儿结局(如早产和死产)相关。对不良结果所涉及的潜在病理生理学和机制的了解有限,以前限制了治疗选择和妊娠管理。这些研究领域的最新进展提供了诱人的目标,以改善受此状况影响的孕妇的护理。 (C)2016 Elsevier Inc.保留所有权利。

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