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首页> 外文期刊>Journal of orthopaedic research >Regenerative medicine in orthopaedic surgery.
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Regenerative medicine in orthopaedic surgery.

机译:骨科手术中的再生医学。

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摘要

Regenerative medicine holds great promise for orthopaedic surgery. As surgeons continue to face challenges regarding the healing of diseased or injured musculoskeletal tissues, regenerative medicine aims to develop novel therapies that will replace, repair, or promote tissue regeneration. This review article will provide an overview of the different research areas involved in regenerative medicine, such as stem cells, bioinductive factors, and scaffolds. The potential use of stem cells for orthopaedic tissue engineering will be addressed by presenting the current progress with skeletal muscle-derived stem cells. As well, the development of a revascularized massive allograft will be described and will serve as a prototypic model of orthopaedic tissue engineering. Lastly, we will describe current approaches used to design cell instructive materials and how they can be used to promote and regulate the formation of bony tissue.
机译:再生医学在骨科手术中具有广阔的前景。随着外科医生继续面对有关患病或受伤的肌肉骨骼组织愈合的挑战,再生医学旨在开发可替代,修复或促进组织再生的新型疗法。这篇综述文章将概述再生医学涉及的不同研究领域,例如干细胞,生物诱导因子和支架。干细胞在骨科组织工程中的潜在用途将通过介绍骨骼肌源性干细胞的最新进展来解决。同样,将描述重新血管化的大规模同种异体移植的发展,并将其作为整形外科组织工程的原型模型。最后,我们将描述当前用于设计细胞指导材料的方法,以及如何将其用于促进和调节骨组织的形成。

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