Psoriasis as a systemic disease

GrozdevI.; KormanN.; TsankovN.

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Psoriasis as a systemic disease

机译：牛皮癣是一种全身性疾病

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Psoriasis is an inflammatory immune-mediated disease that affects the skin and has pathogenic effects with systemic impact. The relationship between psoriasis and comorbidities remains controversial. The hypothesis of a causative role of psoriasis in its cardiovascular and metabolic comorbidities is based on pathophysiologic concepts establishing a link between chronic inflammation in psoriasis, endothelial dysfunction, formation of atherosclerotic plaques, and the different compounds of metabolic syndrome. Psoriasis management has to be multidisciplinary. It implicates identification and treatment of psychological disorders, addictions, and associated cardiovascular and metabolic diseases, together with improvement of quality of life of patients.

机译：牛皮癣是一种炎症性免疫介导的疾病，会影响皮肤，并具有全身性的致病作用。银屑病与合并症之间的关系仍存在争议。牛皮癣在其心血管和代谢合并症中起因的假设是基于病理生理学概念，在牛皮癣的慢性炎症，内皮功能障碍，动脉粥样硬化斑块的形成以及代谢综合征的不同化合物之间建立了联系。银屑病的治疗必须是多学科的。它涉及心理障碍，成瘾以及相关的心血管疾病和代谢性疾病的鉴定和治疗，以及患者生活质量的改善。

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《Clinics in dermatology》 |2014年第3期|共8页
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GrozdevI.; KormanN.; TsankovN.;
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中图分类皮肤病学与性病学;
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1. Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis? [J] . Baker Kenneth F., Isaacs John D. Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2018,第2期

机译：对免疫介导的炎症性疾病的新疗法：我们可以从其在类风湿性关节炎，脊椎炎，全身狼疮红斑狼疮，牛皮癣，克罗恩病和溃疡性结肠炎中学习什么？
2. Systemic Autoimmune, Rheumatic Diseases and Coinciding Psoriasis: Data from a Large Single-Centre Registry and Review of the Literature [J] . AnnaBazsó, PéterSzodoray, ágnesSzappanos, Mediators of inflammation . 2015,第6期

机译：系统性自身免疫，风湿性疾病和牛皮癣重症：来自大型单中心登记处的数据和文献复习
3. Systemic Autoimmune, Rheumatic Diseases and Coinciding Psoriasis: Data from a Large Single-Centre Registry and Review of the Literature [J] . Bazso Anna, Szodoray Peter, Szappanos Agnes, Mediators of inflammation . 2015,第5期

机译：全身自身免疫，风湿病和巧合牛皮癣：来自大型单中心登记处的数据和文献审查
4. Color Space for Psoriasis Skin Diseases Analysis [C] . Rozita Jailani, Mohd Nasir Taib, Saadiah Sulaiman Asian Conference on Sensors . 2003

机译：牛皮癣皮肤病分析的颜色空间分析
5. Best Practice for Screening Adult Patients with Psoriasis for Polyautoimmunity: Celiac Disease, Rheumatoid Arthritis and Crohn's Disease [D] . Ashbaugh, Susan Danielle. 2017

机译：筛查成年多发性银屑病患者的最佳实践：乳糜泻，类风湿关节炎和克罗恩氏病
6. Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits [O] . Daniela Mikhaylov, Peter W. Hashim, Tatyana Nektalova, 2019

机译：牛皮癣患者的全身牛皮癣治疗和合并症：潜在的风险和收益的审查
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Psoriasis as a systemic disease

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